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Theses/Dissertations

2013

Biology

Western University

AtCTD

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Functional Characterization Of The Hua2 Gene Family In Arabidopsis Thaliana, Preetam Janakirama Feb 2013

Functional Characterization Of The Hua2 Gene Family In Arabidopsis Thaliana, Preetam Janakirama

Electronic Thesis and Dissertation Repository

HUA2 encodes a key developmental regulatory protein implicated in the coordination of induction and the maintenance of floral state in Arabidopsis. To gain further insight into the function of HUA2, I have conducted a series of studies aimed at elucidating the molecular function(s) of its individual domains. I show that the PWWP, RPR and CT-proline rich domains within HUA2 are required for the proper regulation of the flowering time phenotype. I also establish that HUA2 interacts with characterized splicing factors (FCA, AtPRP40, RBP45 and UBP1) through its CT-proline rich domain. In addition, I examine the overlap in function between ...