Articles 1 - 1 of 1
Full-Text Articles in Life Sciences
Study Of Genes Relating To Degradation Of Aromatic Compounds And Carbon Metabolism In Mycobacterium Sp. Strain Kms, Chun Zhang
All Graduate Theses and Dissertations
Polycyclic aromatic hydrocarbons, produced by anthropological and natural activities, are hazardous through formation of oxidative radicals and DNA adducts. Growth of Mycobacterium sp. strain KMS, isolated from a contaminated soil, on the model hydrocarbon pyrene induced specific proteins. My work extends the study of isolate KMS to the gene level to understand the pathways and regulation of pyrene utilization. Genes encoding pyrene-induced proteins were clustered on a 72 kb section on the KMS chromosome but some also were duplicated on plasmids. Skewed GC content and presence of integrase and transposase genes suggested horizontal transfer of pyrene-degrading gene islands that also ...