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Presence And Function Of Tetrodotoxin In Terrestrial Vertebrates And Invertebrates, Amber N. Stokes
All Graduate Theses and Dissertations
Tetrodotoxin (TTX) is a potent neurotoxin that acts by blocking the pore region of voltage-gated sodium channels in nerve and muscle tissue. This causes paralysis, and often death due to asphyxiation. Interestingly, TTX is found in an array of organisms ranging from bacterial species to vertebrates. Further, TTX is found in both aquatic and terrestrial environments. This range of taxa and environments has led to three common lines of study for ecological research on this toxin: production, predation, and identification of novel TTX bearing taxa. I began my research by also refining a Competitive Inhibition Enzymatic Immunoassay technique for fast ...