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Chemopreventive Effects Of Cranberry In Association With The Alteration Of Gut Microbiota, Xiaokun Cai Nov 2016

Chemopreventive Effects Of Cranberry In Association With The Alteration Of Gut Microbiota, Xiaokun Cai

Doctoral Dissertations

Accumulating evidence showed that microbiota play important roles in colonic inflammation and inflammation-associated colon carcinogenesis. Fruits and vegetable are known to have protective effects against colon carcinogenesis. Cranberry fruit contains large amount of flavonoids, phenolic acids and dietary fiber, which has been studied for their potential chemopreventive effect from in vitro model. To better understand the effect, we studied the protective effects of whole cranberry powder against colitis in mice treated with dextran sulfate sodium (DSS) and inflammation-associated colon carcinogenesis in mic treated with azoxymethane (AOM) and DSS, and its impact on gut microbiota.

In DSS-induced colitis mice model, 1 ...


Expansion Of And Reclassification Within The Family Lachnospiraceae, Kelly N. Haas Nov 2016

Expansion Of And Reclassification Within The Family Lachnospiraceae, Kelly N. Haas

Doctoral Dissertations

Many of the taxa in the family Lachnospiraceae are currently misclassified as Clostridium spp. Here attempt to rectify many of these issues, beginning with an in-depth genomic and physiologic analysis of Clostridium methoxybenzovorans, culminating in the assertion that is a heterotype of Clostridium indolis, followed by reclassification of the broader group in which this organism resides. We propose two novel genera, Lacriformis and Enterocloster, to reclassify this clade, this includes reclassification of Clostridium sphenoides, Clostridium indolis, Clostridium saccharolyticum, Clostridium celerecrescens, Clostridium xylanolyticum, Clostridium algidixylanolyticum, Clostridium aerotolerans, Clostridium amygdalinum, and Desulfotomaculum guttoideum as Lacriformis sphenoides, comb. nov., Lacriformis indolis, comb. nov ...


The Consequences Of Speed: Studies Of Cavitation During The Mantis Shrimp Strike And The Control Of Rapid Deceleration During Toad Landing, Suzanne M. Cox Nov 2016

The Consequences Of Speed: Studies Of Cavitation During The Mantis Shrimp Strike And The Control Of Rapid Deceleration During Toad Landing, Suzanne M. Cox

Doctoral Dissertations

There are consequences of moving quickly in this world. Here we investigate how two very different species, mantis shrimp (Odontodactylus scyllarus) and cane toads (Bufo marinus), negotiate forces that result from moving rapidly in different environments. To study the mechanical principles and fluid dynamics of ultrafast power-amplified systems, we built Ninjabot, a physical model of the extremely fast mantis shrimp. While mantis shrimp produce damaging cavitation upon impact with their prey, they do not cavitate during the forward portion of their strike despite extreme speeds. In order to study cavitation onset in non-linear flows common during the mantis shrimp strike ...


Distribution And Population Dynamics Of Ungulates In The Mongolian Gobi, Buuveibaatar Bayarbaatar Dr Nov 2016

Distribution And Population Dynamics Of Ungulates In The Mongolian Gobi, Buuveibaatar Bayarbaatar Dr

Doctoral Dissertations

The Mongolian Gobi is one of the most spectacular and important regions in Central Asia, comprising the largest area of intact grassland in the world. In recent years, a growing human population, expanding exploitation of natural resources, and the development of infrastructure in the region place increasing pressure on these species and their habitats. This dissertation has focused on three species of ungulates such as Mongolian saiga (Saiga tatarica mongolica) in western Mongolia, and Asiatic wild ass (Equus hemionus), and goitered gazelle (Gazella subgutturosa) in Southern Gobi. The study on endangered saiga antelope in western Mongolia found that the calving ...


The Neural Correlates Of Emotion Reactivity And Regulation In Young Children With Adhd, Claudia I. Lugo-Candelas Nov 2016

The Neural Correlates Of Emotion Reactivity And Regulation In Young Children With Adhd, Claudia I. Lugo-Candelas

Doctoral Dissertations

Attention-deficit hyperactivity disorder (ADHD) is the most frequently occurring pediatric neurobehavioral disorder. Although emotion reactivity and regulation are frequently impaired in ADHD, few studies have examined these factors in preschool aged children with ADHD, and none have explored the neural correlates of emotion reactivity and regulation in this group though event-related potentials (ERPs). Children aged 4 to 7 with (n = 24) and without (n = 30) ADHD symptoms completed an attention task composed of four blocks: baseline, frustration, suppression, and recovery. In the frustration and suppression blocks, negative affect was induced by false negative feedback. During the suppression block, children were ...


Evaluating Resistance Surfaces For Modeling Wildlife Movement And Connectivity, Katherine Zeller Nov 2016

Evaluating Resistance Surfaces For Modeling Wildlife Movement And Connectivity, Katherine Zeller

Doctoral Dissertations

The continued growth of human populations and associated development in many areas of the world is causing persistent fragmentation of natural habitats. In response, wildlife corridors are often promoted as essential for the conservation of wildlife species. Wildlife corridors allow for the movement of individuals between habitat patches and confer many benefits including the maintenance of metapopulations and metapopulation dynamics, the maintenance of seasonal migratory routes, genetic exchange, and the potential for individuals and populations to shift their ranges in response to climate change.

Wildlife corridors are modeled across a resistance-to-movement surface where resistance represents the willingness of an organism ...


X-Ray Characterization Of Mesophases And Phase Transitions Of Dna Analogues In Solutions, Mustafa Selcuk Yasar Nov 2016

X-Ray Characterization Of Mesophases And Phase Transitions Of Dna Analogues In Solutions, Mustafa Selcuk Yasar

Doctoral Dissertations

We think of DNA as double-stranded helices (duplex), but the polymer exists in many conformations. Several triplex and quadruplex DNA structures can be formed in laboratory settings and exist in nature. This thesis first provides a brief description of the nature of the order in arrays of duplex DNA under biologically relevant molecular crowding conditions. Then we compare the duplex DNA mesophases with the corresponding liquid crystalline phase behavior of the triplex and quadruplex DNA analogues. In particular, we focus on G-quadruplexes.

Observed in the folds of guanine-rich oligonucleotides, G-quadruplex structures are based on G-quartets formed by hydrogen bonding and ...


Regional Recruitment Dynamics And Seasonal Ecology Of Juvenile Bluefish (Pomatomus Saltatrix), David G. Stormer Nov 2016

Regional Recruitment Dynamics And Seasonal Ecology Of Juvenile Bluefish (Pomatomus Saltatrix), David G. Stormer

Doctoral Dissertations

Recruitment in fishes, defined as the survival of a cohort through the first year of life, can be highly variable and affected by small changes in biological and physical factors. Much of the historical focus into the sources of recruitment variability has concentrated on the larval stage, but recent attention has shifted to the relatively longer juvenile period. Spawning behavior that results in the production of multiple cohorts over time and space within a year-class may dampen recruitment variability by decreasing natural mortality risk. The bluefish (Pomatomus saltatrix) is a migratory marine species that produces multiple cohorts of offspring during ...


Biopolymer Electrospun Nanofiber Mats To Inactivate And Remove Bacteria, Katrina Ann Rieger Nov 2016

Biopolymer Electrospun Nanofiber Mats To Inactivate And Remove Bacteria, Katrina Ann Rieger

Doctoral Dissertations

The persistence of antibiotic resistance in bacterial pathogens remains a primary concern for immunocompromised and critically-ill hospital patients. Hospital associated infections can be deadly and reduce the successes of medical advancements, such as, cancer therapies and medical implants. Thus, it is imperative to develop materials that can (i) deliver new antibiotics with accuracy, as well as (ii) uptake pathogenic microbes. In this work, we will demonstrate that electrospun nanofiber mats offer a promising platform for both of these objectives because of their high surface-to-volume ratio, interconnected high porosity, gas permeability, and ability to contour to virtually any surface. To provide ...


Label-Free And Aptamer-Based Surface Enhanced Raman Spectroscopy For Detection Of Food Contaminants, Shintaro Pang Nov 2016

Label-Free And Aptamer-Based Surface Enhanced Raman Spectroscopy For Detection Of Food Contaminants, Shintaro Pang

Doctoral Dissertations

The development of analytical methods to detect food contaminants is a critical step for improving food safety. Surface enhanced Raman spectroscopy (SERS) is an emerging detection technology that has the potential to rapidly, accurately and sensitively detect a wide variety of food contaminants. However, SERS detection becomes a challenge in real complex matrix, such as food, since non-specific matrix signals have the potential to drown out target associated Raman peaks. In this dissertation, we focused on the development and application of label-free, aptamer-based SERS in order to improve the accuracy and specificity of target contaminant detection in food. To accomplish ...


Bacteriophage-Based Colorimetric Detection Of Escherichia Coli In Drinking Water, Juhong Chen Nov 2016

Bacteriophage-Based Colorimetric Detection Of Escherichia Coli In Drinking Water, Juhong Chen

Doctoral Dissertations

One of the major safety causes in drinking water is from the bacteria contamination, especially in developing countries and resource-limited settings. Although many of these Escherichia coli (E. coli) strains in drinking water are nonpathogenic, they sever as the indicator for bacterial contamination. And, the more widely used method to detect E. coli in drinking water is to determine the activity of β-galactosidase (β-gal), which is released by E. coli. Rapid, sensitive and inexpensive detection of E. coli in drinking water can reduce the risk of food-borne bacteria infection and stop the disease widely spreading.

In this degree research, phage-based ...


Characterizing Colorectal Cancer Cells And Their Interactions With Polymethoxyflavones By Raman Microscopy, Hua Zhang Nov 2016

Characterizing Colorectal Cancer Cells And Their Interactions With Polymethoxyflavones By Raman Microscopy, Hua Zhang

Doctoral Dissertations

Polymethoxyflavones (PMFs), especially Nobiletin (NBT) and 5-demethylnobiletin (5DN), have been widely studied and proved to have anti-cancer effects. However, their exact modes of action against cancer cells are not fully understood. Raman spectroscopy is a molecular vibrational spectroscopy can be used to measure overall biochemical function of single cells noninvasively and without adding any chemical labels. Herein, we characterized the cellular responses of human colorectal cancer HT29 and HCT116 cells, that grow on the gold coated slides, to the treatments of NBT and 5DN using Raman microscopy. Raman microscopic images obtained indicated the different modes of action of these two ...


Effects Of Adolescent Alcohol Binge Drinking On Prefrontal Myelin, Wanette M. Vargas-Rodriguez Nov 2016

Effects Of Adolescent Alcohol Binge Drinking On Prefrontal Myelin, Wanette M. Vargas-Rodriguez

Doctoral Dissertations

Alcohol binge drinking is highly prevalent in teenagers and is associated with various harmful health effects and social problems. During adolescence, brain regions such as the prefrontal cortex (PFC) are still undergoing active development, characterized by increases in white matter volume. While the morphological details and the cellular and molecular sequences governing adolescent white matter development are not fully known, it is known that this development process is sensitive and can be disrupted. Although consumption of alcohol in a binge drinking pattern has been linked to lower white matter integrity in humans, it is important to determine if alcohol is ...


Evaluating Digital Vhf Technology To Monitor Shorebird And Seabird Use Of Offshore Wind Energy Areas In The Western North Atlantic, Pamela H. Loring Nov 2016

Evaluating Digital Vhf Technology To Monitor Shorebird And Seabird Use Of Offshore Wind Energy Areas In The Western North Atlantic, Pamela H. Loring

Doctoral Dissertations

Information on offshore movements of high priority bird species is needed for monitoring and managing adverse effects of offshore wind energy development in the western North Atlantic Ocean. This information is particularly important at night and during periods of inclement weather when risks of collision with offshore wind turbines may be elevated. For small-bodied avian taxa, technologies for monitoring movements of individually-marked birds are limited since satellite-based devices are still too heavy (> 5 g) for use on birds weighing < 150 g. In this dissertation, I evaluate the use of light-weight (1 to 1.5 g) digital VHF transmitters and a network of automated radio telemetry stations for tracking shorebirds and seabirds in offshore areas. In Chapter One, I compare digital VHF telemetry with satellite telemetry for tracking a shorebird, the American Oystercatcher (Haematopus palliatus), at nesting areas in coastal Massachusetts. In Chapter Two, I evaluate possible adverse effects and retention time of using ...


Alterations To Maternal Behavior And Brain By Exogenous Estrogen Exposure, Mary Catanese Nov 2016

Alterations To Maternal Behavior And Brain By Exogenous Estrogen Exposure, Mary Catanese

Doctoral Dissertations

Maternal care is critical for the development and long-term success of offspring. Poor maternal care can have profound effects on offspring that can last into adult life. Despite our understanding of the role of endogenous estrogen in maternal behavior, the potential effects of exogenous estrogens (xenoestrogens) on maternal behavior and brain remain poorly understood.

The active synthetic estrogen in contraceptive pills, 17α-ethinyl estradiol (EE2), is widely used as a positive control for estrogenicity in endocrinology and toxicology studies. Another xenoestrogen, bisphenol A (BPA) alters a broad range of physiological processes including neural development and reproduction. Due to public health concerns ...


The Cellular Context Of Estradiol Regulation In The Zebra Finch Auditory Forebrain, Maaya Ikeda Nov 2016

The Cellular Context Of Estradiol Regulation In The Zebra Finch Auditory Forebrain, Maaya Ikeda

Doctoral Dissertations

Estradiol, traditionally known as a hormone that communicates with distant cells in the body, is also synthesized locally in the brain to act as a neuromodulator. Neuromodulators differ from neurotransmitters in that they simultaneously affect a population of neurons and their actions are not limited to the synapse. One of the many effects of estradiol signaling is rapid modulation of auditory processing in response to external stimuli. The enzyme required for estradiol synthesis, aromatase, is highly expressed in the regions that are involved in higher-order processing of sounds in humans and songbirds. Since zebra finches, a type of songbird, are ...


Investigating The Impact Of Small Molecule Ligands And The Proteostasis Network On Protein Folding Inside The Cell, Karan Hingorani Nov 2016

Investigating The Impact Of Small Molecule Ligands And The Proteostasis Network On Protein Folding Inside The Cell, Karan Hingorani

Doctoral Dissertations

The folded forms of most proteins are critical to their functions. Despite the complexity of the cellular milieu and the presence of high-risk deleterious interactions, there is a high level of fidelity observed in the folding process for entire proteomes. Two important reasons for this are the presence of the quality control machinery consisting of chaperones and degradation enzymes that work jointly to optimize the population of the folded state and interaction partners that re-enforce the functional state and add to the competitive advantage of an organism. While substantial effort has been directed to understand protein folding and interactions in ...


Functionalized Electrospun Nanofibers For Food Science Applications, Minhui Dai Jul 2016

Functionalized Electrospun Nanofibers For Food Science Applications, Minhui Dai

Doctoral Dissertations

This work is separated into two individual parts. The first part demonstrates the ability to electrospin reagents into water-soluble nanofibers resulting in a stable on-chip enzyme and a microphage storage format.

1a) Polyvinylpyrrolidone (PVP) nanofibers were spun incorporating the enzyme horseradish peroxidase (HRP). Scanning electron microscopy of the spun nanofibers was used to confirm the non-woven structure with an average diameter of 155±34 nm. The HRP containing fibers were tested for a change in activity following electrospinning and during storage. A colorimetric assay was used to characterize the activity of HRP reacting with the nanofiber mats in a microtiter ...


Inhibition Of Dna Methylation In Acquired Tamoxifen-Resistant Breast Cancer: Cell Line Model And Clinical Implications, Stephanie Zimmers Jul 2016

Inhibition Of Dna Methylation In Acquired Tamoxifen-Resistant Breast Cancer: Cell Line Model And Clinical Implications, Stephanie Zimmers

Doctoral Dissertations

One out of every eight American women will develop invasive breast cancer throughout their lifetime. Approximately 70% of breast cancers are estrogen receptor alpha (ER)-positive and can therefore be treated with an anti-estrogen such as tamoxifen. Although tamoxifen treatment has been successful at reducing breast cancer death rates, nearly one-third of women treated with tamoxifen for 5 years will have disease recurrence. Therefore, it is imperative that researchers investigate the mechanisms involved in developing acquired tamoxifen resistance and identify biomarkers that are predictive of acquired resistance.

DNA methylation is known to play a role in the development of breast ...


Spider Brain Morphology & Behavior, Skye M. Long Jul 2016

Spider Brain Morphology & Behavior, Skye M. Long

Doctoral Dissertations

Spiders are ideal model animals for experimental and comparative studies of behavior, learning and perception. They display many complex behaviors, such as the multimodal mating dances of lycosid spiders, the stealthy hunting strategies of the jumping spider Portia sp., to the labile sociality of theridiids. Spiders also demonstrate a wide range of cognitive capabilities. Spiders perceive their environment using multiple sensory modalities including: chemosensory organs; lyriform and slit-sense organs and specialized hairs that detect vibration and air movement; and up to eight eyes that vary in function, some able to detect polarization and a broad spectrum of light, including ultraviolet ...


Alternative Methods For The Treatment Of Chemo-Resistant Cancers, Kaitlyn Wong Jul 2016

Alternative Methods For The Treatment Of Chemo-Resistant Cancers, Kaitlyn Wong

Doctoral Dissertations

Great strides have been made in cancer therapy in the past century, yet it remains one of the leading causes of death in the United States today. This work aimed to shed light on novel methods to treat a variety of aggressive and often chemo-resistant cancers both in vitro and in vivo.

The first aim of this work was to evaluate the therapeutic efficacy of poly(methacryloyloxyethyl phosphorylcholine) (polyMPC) prodrugs compared to standard chemotherapeutic agents. Conjugation of polyMPC to drugs such as doxorubicin (Dox) can result in its improved solubility, prolonged half-life and therapeutic efficacy. PolyMPC and polyMPC-Dox (at a ...


Macronutrients And The Risk Of Premenstrual Syndrome, Serena C. Houghton Jul 2016

Macronutrients And The Risk Of Premenstrual Syndrome, Serena C. Houghton

Doctoral Dissertations

Premenstrual syndrome (PMS) affects 8-20% of reproductive-aged women, impacting work, family, and social interactions. Limitations in available PMS treatments, including side effects and limited medication efficacy, indicate the need for improved prevention. Modifiable risk factors for prevention of PMS include dietary factors. Several micronutrients have been identified as risk factors, but there has been little evaluation of macronutrients. Thus, the research aim was to examine prospectively whether macronutrient consumption was associated with PMS development among a subset of women enrolled in the Nurses’ Health Study II cohort.

Chapter 1 evaluates the association of fat intake and PMS risk. Among 3 ...


Morphological And Material Effects In Van Der Waals Interactions, Jaime C. Hopkins Jul 2016

Morphological And Material Effects In Van Der Waals Interactions, Jaime C. Hopkins

Doctoral Dissertations

Van der Waals (vdW) interactions influence a variety of mesoscale phenomena, such as surface adhesion, friction, and colloid stability, and play increasingly important roles as science seeks to design systems on increasingly smaller length scales. Using the full Lifshitz continuum formulation, this thesis investigates the effects of system materials, shapes, and configurations and presents open-source software to accurately calculate vdW interactions.

In the Lifshitz formulation, the microscopic composition of a material is represented by its bulk dielectric response. Small changes in a dielectric response can result in substantial variations in the strength of vdW interactions. However, the relationship between these ...


Novel Advancements For Improving Sprout Safety, Kyle S. Landry Jul 2016

Novel Advancements For Improving Sprout Safety, Kyle S. Landry

Doctoral Dissertations

All varieties of bean sprouts (mung bean, alfalfa, broccoli, and radish) are classified as a “super-food” and are common staples for health conscious consumers. Along with the proposed health benefits, there is also an inherent risk of foodborne illness. When sprouts are cooked, there is little risk of illness. The purpose of this dissertation was to explore novel techniques to minimize or prevent the incidence of foodborne illness associated with the consumption of sprouts. Three areas were investigated: 1) the use of a biocontrol organism, 2) the use of a novel spontaneous carvacrol nanoemulsion, and 3) the influence of the ...


The Role Of The Formin Protein Family In Membrane Dynamics, Petrus Adrianus Cornelis Van Gisbergen Jul 2016

The Role Of The Formin Protein Family In Membrane Dynamics, Petrus Adrianus Cornelis Van Gisbergen

Doctoral Dissertations

Using molecular genetics, and high end imaging techniques, I assessed the function of the formin protein family in the moss Physcomitrella patens. Formins are proteins that can nucleate and elongate actin filaments. P. patens has 9 formins, divided over three classes. I found that a class II formin (For2A) is essential for polarized growth and specifically binds to the phosphoinositide PI(3,5)P2. Additionally, I show that this formin polymerizes actin filaments in vivo. I demonstrated that binding PI(3,5)P2 is essential for formin function.

My work also shows that one of the class I ...


The Meat-Farming Ants: Predatory Mutualism Between Melissotarsus Ants (Hymenoptera: Formicidae) And Armored Scale Insects (Hemiptera: Diaspididae), Scott A. Schneider Jul 2016

The Meat-Farming Ants: Predatory Mutualism Between Melissotarsus Ants (Hymenoptera: Formicidae) And Armored Scale Insects (Hemiptera: Diaspididae), Scott A. Schneider

Doctoral Dissertations

Ant agricultural mutualisms are common, well studied, and receive attention from scientific and public spheres due to shared similarities with human agriculture (i.e. ant/fungus ‘crop farming’ and ant/insect ‘dairy farming’). They also serve as important model systems for studying many facets of mutualism. This study reveals that the repertoire of ant agriculture may also include ‘meat farming’. Predatory mutualisms occur between Melissotarsus ants and various species of armored scale insects. This dissertation employs a multi-disciplinary approach to investigate the evolutionary history and nature of ant/diaspidid mutualisms. Chapter 1 reviews the current state of knowledge regarding species ...


Synthesis And Applications Of Non-Migratory Metal Chelating Active Packaging, Maxine J. Roman Jul 2016

Synthesis And Applications Of Non-Migratory Metal Chelating Active Packaging, Maxine J. Roman

Doctoral Dissertations

Many packaged foods use synthetic chelators (e.g. ethylenediaminetetraacetic acid, EDTA) to inhibit metal promoted oxidation and/or microbial growth that may cause food spoilage. Consumer demand for foods without synthetic additives has prompted growing interest in alternative preservation methods. Our research group has previously developed non-migratory metal chelating active packaging materials by surface immobilization of polymeric chelators and demonstrated their ability to inhibit lipid oxidation in model food emulsions. The work presented in this dissertation investigates the synthesis, performance stability, and practical application of metal chelating surface modifications to optimize design of non-migratory metal chelating active packaging materials.

Metal ...


Enzyme Stabilization In Hierarchical Biocatalytic Food Packaging And Processing Materials, Dana Erin Wong Jul 2016

Enzyme Stabilization In Hierarchical Biocatalytic Food Packaging And Processing Materials, Dana Erin Wong

Doctoral Dissertations

The partnership of biocatalysts and solid support materials provides many opportunities for bioactive packaging and bioprocessing aids beneficial to the agricultural and food industries. Biocatalysis, or reactions modulated by enzymes, allows bioactive materials to assist in bringing a substrate to product. Enzymes are proteins which catalyze reactions by lowering the activation energy required to drive the production of a desired product. Enzymes are commonly utilized in food processing as catalysts with specificity in order to enhance product quality through the production of beneficial food components, and to break down undesirable components that may be harmful or may decrease product quality ...


Chemically Mediated Interactions Between Hosts, Parasitic Plants And Insect Herbivores, Muvari C. Tjiurutue Jul 2016

Chemically Mediated Interactions Between Hosts, Parasitic Plants And Insect Herbivores, Muvari C. Tjiurutue

Doctoral Dissertations

Species interactions, by changing phenotypic traits, can alter the outcome of subsequent interactions. Plant-mediated responses to herbivores have been extensively studied, but little is known about plant-mediated responses involving parasitic plants within a broader community context that also includes herbivores. Because parasitic plants are important components of many ecosystems and can shape community structure, it is important to understand how host-mediated interactions influence parasite preference and success. The goal of this thesis is to examine interactions between hosts, parasitic plants and herbivores mediated by chemical traits. We first examined the effects of dodder (Cuscuta sp.) parasitism on induced defenses in ...


Feasibility Of A Combined Physical Activity And Sleep Education Intervention For Girls Living In A Low Socioeconomic Status Urban Community, Cory J. Greever Jul 2016

Feasibility Of A Combined Physical Activity And Sleep Education Intervention For Girls Living In A Low Socioeconomic Status Urban Community, Cory J. Greever

Doctoral Dissertations

Declining sleep duration and poor sleep quality is a public health epidemic disproportionately effecting elementary age girls living in low socioeconomic status urban communities. The Girls Dancing and Sleeping for Health (Girls DASH) program was designed to test the feasibility, acceptability, and efficacy of a combined physical activity and sleep education program in this population. In combination with baseline data from a previously conducted intervention in elementary age urban girls living in a low SES community in Springfield, MA, results from a cross-sectional analysis indicated that greater screen time was positively associated with parental reports of child’s sleep quality ...