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Theses/Dissertations

University of Massachusetts Amherst

1995

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Full-Text Articles in Life Sciences

Zinc Metabolism In The Streptozotocin (Stz)-Diabetes, Aizhong Fu Feb 1995

Zinc Metabolism In The Streptozotocin (Stz)-Diabetes, Aizhong Fu

Doctoral Dissertations 1896 - February 2014

Hyperzincuria in diabetics has been regarded as the culprit depleting body zinc stores. Studies were designed to assess rates of 65Zn absorption and retention as a possible compensation mechanism; to assess zinc concentrations and distribution among body compartments, and to assess the kinetics of 65Zn metabolism in STZ-diabetic rats. The rates of 65Zn absorption and retention were not significantly different between STZ-diabetic and control rats. However, STZ-diabetic rats had significantly higher rates of 65Zn absorption (16.88%) and retention (34.36%) when they were "Post-fasted" than when they were "Prior-fasted" (9.04% and 18.68% respectively). These differences were also ...