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Integrating Social Dimensions Into Spatial Connectivity Planning For Grizzly Bears, Abigail Sage Dec 2019

Integrating Social Dimensions Into Spatial Connectivity Planning For Grizzly Bears, Abigail Sage

Boise State University Theses and Dissertations

In anthropogenic landscapes, which prevail globally, preserving key habitat corridors or routes between wildlife populations is vital for long-term species persistence. Animals moving through these corridors can encounter a number of barriers, including roads, fences, or other human land-uses. Additionally, people unwilling to cohabitate with wildlife can also kill animals considered nuisances or disturb animals in ways that reduce their fitness. The spatial patterns of human tolerance therefore play an important role in the efficacy of habitat corridors. Although there are large bodies of research on habitat corridors and human attitudes toward wildlife, studies that examine the spatial interaction of ...


Comprehensive Investigation Of Bioactive Steroidal Alkaloids In Veratrum Californicum, Matthew West Turner Dec 2019

Comprehensive Investigation Of Bioactive Steroidal Alkaloids In Veratrum Californicum, Matthew West Turner

Boise State University Theses and Dissertations

Veratrum californicum, commonly referred to as corn lily or Californian false hellebore, grows in high mountain meadows and produces bioactive steroidal alkaloids, including cyclopamine. Cyclopamine is a potent inhibitor of the Hedgehog (Hh) signaling pathway. Our lab has optimized methods to extract cyclopamine and related steroidal alkaloids from V. californicum, and implemented in-house Hh signaling bioactivity evaluation of these steroidal alkaloids using a Shh-Light II cell assay. A survey of extraction methods and solvents resulted in the identification of conditions most favorable for alkaloid extraction yield and antagonist activity in the Shh-Light II cell assay. The highest amount of bioactive ...


Informing Field Management Decisions To Enhance Alfalfa Seed Production Using Remote Sensing, Thomas V. Van Der Weide Dec 2019

Informing Field Management Decisions To Enhance Alfalfa Seed Production Using Remote Sensing, Thomas V. Van Der Weide

Boise State University Theses and Dissertations

The development rate of alfalfa seed crop depends on both environmental conditions and management decisions. Crop management decisions, such as determining when to release pollinators to optimize pollination, can be informed by the identification of plant development stages from remote sensing data. I first identify what electromagnetic wavelengths are sensitive to alfalfa plant development stages using hyperspectral data. A Random Forest regression is used to determine the best Vegetation Index (VI) to monitor how much of the plant is covered in flower. The results indicate that Blue, Green, and Near-Infrared are the important electromagnetic wavelengths for the VI. Imagery collected ...


Structure And Bioactivity Of A Rationally Designed Nicotinic Acetylcholine Receptor Antagonist Targeting The Alpha-3 Beta-2 Subtype, Leanna Marquart Dec 2019

Structure And Bioactivity Of A Rationally Designed Nicotinic Acetylcholine Receptor Antagonist Targeting The Alpha-3 Beta-2 Subtype, Leanna Marquart

Boise State University Theses and Dissertations

The work presented in this thesis contributes to ongoing development of an efficient workflow for identification of lead compounds, based on the molecular scaffold of α-conotoxin MII, for drug therapies targeting nicotinic acetylcholine receptors. Nicotinic acetylcholine receptors (nAChRs) are pentameric, ligand-gated ion channels with distribution throughout the central nervous system and are implicated in a variety of neurological diseases including schizophrenia, nicotine addiction, Alzheimer’s disease, and Parkinson’s disease. However, ligand effect on nAChR function is not well understood. Consequently, drug therapies for neurological diseases either do not exist, or have short-lasting efficacy and/or severe side effects. Barriers ...


Acute Exposure To Tcdd Increases Liver Disease Progression In Mice With Carbon Tetrachloride-Induced Liver Injury, Giovan N. Cholico Dec 2019

Acute Exposure To Tcdd Increases Liver Disease Progression In Mice With Carbon Tetrachloride-Induced Liver Injury, Giovan N. Cholico

Boise State University Theses and Dissertations

Liver disease is a worldwide problem and the 9th leading cause of death in the United States. Common causes of liver disease include alcohol abuse, virus infection, and nonalcoholic fatty liver. Regardless of etiology, liver damage elicits inflammation and drives the activation of hepatic stellate cells (HSCs), which deposit collagen throughout the liver. During chronic injury, excessive collagen deposition, referred to as fibrosis or “scarring”, can progress to cirrhosis, cancer, and organ failure. Emerging evidence indicates a strong association between liver disease and exposure to environmental chemicals. This research investigated mechanisms by which exposure to the environmental contaminant 2 ...


Effects Of Protective Nesting Site Properties On Gyrfalcon Breeding Success And Parental Investment In Western Alaska, Michael Thomas Henderson Aug 2019

Effects Of Protective Nesting Site Properties On Gyrfalcon Breeding Success And Parental Investment In Western Alaska, Michael Thomas Henderson

Boise State University Theses and Dissertations

Habitat suitability for wildlife is defined at scales ranging from the landscape to an individual breeding site. Areas that fulfill habitat requirements for birds disproportionally maintain populations, and the identification of variables that distinguish optimal breeding sites helps to prioritize conservation. Nesting site characteristics that protect breeding raptors from harsh weather can promote a more favorable microclimate and increase breeding success, although previous attempts to understand this effect in breeding Gyrfalcons have yielded ambiguous results. Additionally, breeding adults incur substantial costs from the physical shielding of eggs and nestlings, particularly in the Arctic, and it is possible that protective properties ...


Genetic Variability Of Cultivars Shape Biochemical Profiles In A Bioenergy Cropping System, Megan Kelly-Slatten Aug 2019

Genetic Variability Of Cultivars Shape Biochemical Profiles In A Bioenergy Cropping System, Megan Kelly-Slatten

Boise State University Theses and Dissertations

The largest terrestrial carbon (C) pool on Earth is the soil, surpassing both biotic and atmospheric C pools combined. The majority of C stabilized in soil is root-derived, and root derived C is the preferred food source for the soil microbial community. Recent studies have indicated that the perennial bioenergy crops Panicum Virgatum (hereafter: switchgrass) and Andropogon Gerardii (hereafter: big bluestem) accumulate significant amounts of soil C owing to their extensive root systems, and that soil C accumulation rates are driven by inter- and intra-specific variability in plant traits. While soil C accumulation in the short term (i.e. after ...


Methodological Advances For Understanding Social Connectivity And Environmental Implications In Multi-Use Landscapes, Matthew Clark Aug 2019

Methodological Advances For Understanding Social Connectivity And Environmental Implications In Multi-Use Landscapes, Matthew Clark

Boise State University Theses and Dissertations

Integrated social-ecological systems research is challenging; complicated feedback and interactions across scales in multi-use landscapes are difficult to decouple. Novel methods and innovative data sources are needed to advance social-ecological systems research. In this thesis, we use network science as a means of explicitly assessing feedback between social and ecological systems, and internet search data to better predict visitation in protected areas. This thesis seeks to provide empirical examples of emerging social-ecological systems science methods as a precedent for resource managers on-the-ground, as well as extending the line of scientific inquiry on the subject

In the first chapter of this ...


Early Changes In Memory, Motor Coordination And Strength In The Transgenic Rat Model Of Alzheimer’S Disease, Tgf344-Ad, Mark Andrew Winslow Aug 2019

Early Changes In Memory, Motor Coordination And Strength In The Transgenic Rat Model Of Alzheimer’S Disease, Tgf344-Ad, Mark Andrew Winslow

Boise State University Theses and Dissertations

Introduction: Alzheimer’s disease (AD) is the most common form of dementia and an estimated 5.7 million American’s are currently suffering from this disease resulting in $277 billion in health care costs as of 2018. As the number of cases and cost are expected to double by 2050, new approaches are needed to properly identify at-risk individuals prior to irreversible changes to the brain caused by this disease. Purpose: Through the use of a novel rodent model, this study assessed early changes in muscular coordination and strength relative to cognitive decline due to AD, as well as providing ...


Validity Of The Polar M430 Among Females Of Varying Fitness Levels, Body Fat Percentage, And Reported Physical Activity, Kevin Earl Miller Aug 2019

Validity Of The Polar M430 Among Females Of Varying Fitness Levels, Body Fat Percentage, And Reported Physical Activity, Kevin Earl Miller

Boise State University Theses and Dissertations

Introduction: The Polar M430 is a heart rate monitor that uses a non-exercise prediction method to predict one’s V̇O2max. Research has revealed that this method will overestimate predicted V̇O2max among females. Studies have investigated the validity of this method, however, these studies have not taken into account how physical activity (PA) levels, body fat percentage, or measured V̇O2max could affect the prediction value. Purpose: The purpose of this study was to investigate the validity of the Polar M430 in predicting V̇O2max amongst females of varying PA levels, body fat percentages, and ...


Intraspecific Variation In Plant-Plant Interactions And Belowground Zone Of Influence Of Big Sagebrush (Artemisia Tridentata), Andrii Zaiats May 2019

Intraspecific Variation In Plant-Plant Interactions And Belowground Zone Of Influence Of Big Sagebrush (Artemisia Tridentata), Andrii Zaiats

Boise State University Theses and Dissertations

Post-fire restoration of degraded sagebrush ecosystems over large areas of the Great Basin is challenging, in part due to unpredictable outcomes. Low rates of restoration success are attributed to increasing frequencies of wildfires, biological invasions, and climate variability. Quantifying restoration outcomes by accounting for sources of biotic and abiotic variability will improve restoration as a predictive science. One source of biotic variability is neighbor interactions, which can regulate demographic parameters of coexisting species and are an important determinant of community structure, ecosystem functions, and population dynamics. Our objective was to quantify how intraspecific variability in big sagebrush, Artemisia tridentata, including ...


The Relationship Between Perfectionism And Self-Determined Motivation In Collegiate Division I Athletes, Christian Sengfelder May 2019

The Relationship Between Perfectionism And Self-Determined Motivation In Collegiate Division I Athletes, Christian Sengfelder

Boise State University Theses and Dissertations

Introduction: An athlete’s performance is dependent on both psychological and physical factors. Perfectionism and motivation are two psychological factors that can influence performance of athletes in a positive or negative manner. The relationship between perfectionism and motivation has been studied previously, but the relationship has not been studied with sport specific measurements and the collegiate athlete population has largely been ignored. Purpose: To investigate the levels of perfectionism and motivation in collegiate Division I student-athletes and determine how the forms of perfectionism (adaptive versus maladaptive) are related to the different levels of motivation (controlled vs autonomous forms) in this ...


Apnea Training And Physical Characteristics: Enhancement Of The Dive Response, Apneic Time, And Recovery, Nathanael Stanford May 2019

Apnea Training And Physical Characteristics: Enhancement Of The Dive Response, Apneic Time, And Recovery, Nathanael Stanford

Boise State University Theses and Dissertations

Human breath-hold diving (free diving) has been gaining popularity as new individuals participate in the sport every year. Carbon dioxide (CO2) breath-hold tables have been widely implemented as a training modality and prescribe constant submaximal apneic durations with gradually decreasing recovery times to increase hypercapnic resiliency. Previous studies implementing maximal duration apnea training have found enhancements in apneic duration and the mammalian dive reflex (MDR), which is elicited by apnea and augmented with facial immersion. The MDR results in bradycardia and peripheral vasoconstriction to redistribute blood to vital organs and elicit oxygen (O2) conserving resulting in prolonged apneas ...


Investigating Autophagy Dysfunction Induced By A Parkinson's Disease-Causing Mutation In Vps35, Abir Ashfakur Rahman Dec 2018

Investigating Autophagy Dysfunction Induced By A Parkinson's Disease-Causing Mutation In Vps35, Abir Ashfakur Rahman

Boise State University Theses and Dissertations

Parkinson’s Disease (PD) is an idiopathic disorder with no known cure. With number of cases steadily rising around the world, it is imperative to turn to the underlying cellular and molecular mechanisms of the disease manifestation and neurodegeneration to craft novel modes of therapy. VPS35 is one of the few genes that have identified and definitively linked to familial PD. The particular mutation that has been associated is known to cause dysfunction of a key cellular process known as autophagy. This process is primarily responsible for clearance of unwanted, damaged or misfolded proteins, among other things. Our study reveals ...


Novel Regulatory Pathways Of Protein Channels, Sheenah Lynn Bryant Dec 2018

Novel Regulatory Pathways Of Protein Channels, Sheenah Lynn Bryant

Boise State University Theses and Dissertations

Since the proposal of the fluid mosaic model of a cell membrane, substantial scientific evidence has shown that the cell membrane is not simply an inert structure with the sole role of separating two chemically different environments. The cell membrane dynamically satisfies basic needs, such as water, ion and nutrient transport, without which the cell could not survive. It is a structure which actively participates in a great variety of physiological functions. The activity of the cell membrane is responsible for the contraction of our muscles and information processing in our brain. In order to participate in such a wide ...


A Human-Environment Systems Approach To Outdoor Recreation, Human Biological Stress, And Landscape Aesthetics, Ellie Dawn Opdahl Aug 2018

A Human-Environment Systems Approach To Outdoor Recreation, Human Biological Stress, And Landscape Aesthetics, Ellie Dawn Opdahl

Boise State University Theses and Dissertations

Outdoor recreation, as the intersection between physical exercise and nature, provides a multitude of psychological and physiological benefits to human well-being. Though many studies have reported qualitative stress reduction from outdoor recreation, few have focused on quantitative measurements of stress across recreational activity types, intrapersonal differences, and environmental variables. To determine whether outdoor recreation affects physiology, we collected 190 paired salivary cortisol and testosterone samples and 157 surveys from 88 hikers, 81 mountain bikers, and 44 off-highway vehicle (OHV) motorists. After recreation, cortisol concentrations were significantly reduced in hikers and OHV motorists, but cortisol and testosterone concentrations increased in mountain ...


Building The Full Annual Cycle Picture For Long-Billed Curlews: Correlates Of Nest Success In The Breeding Grounds And Spatial Distribution And Site Fidelity In The Wintering Grounds, Stephanie E. Coates May 2018

Building The Full Annual Cycle Picture For Long-Billed Curlews: Correlates Of Nest Success In The Breeding Grounds And Spatial Distribution And Site Fidelity In The Wintering Grounds, Stephanie E. Coates

Boise State University Theses and Dissertations

Migratory birds face threats throughout the annual cycle, and cumulative effects from linkages between the breeding and non-breeding grounds may impact species at the population level. Long-billed Curlews (Numenius americanus) are a migratory shorebird of conservation concern associated with grasslands that show breeding population declines at some regional and local scales. Curlews exhibit high site fidelity to breeding territories, but also spend approximately 75% of the year on the wintering grounds. Therefore, localized population declines could indicate localized threats, in the breeding or wintering grounds. However, little information is available regarding the spatial distribution of curlews on the wintering grounds ...


Transitioning Out Of Sport: Perspectives Of Student-Athlete Support Or Development Services, Alison Ohashi May 2018

Transitioning Out Of Sport: Perspectives Of Student-Athlete Support Or Development Services, Alison Ohashi

Boise State University Theses and Dissertations

Introduction: Despite the substantial amount of literature on career transitions in sport, there is insufficient research examining the social support system within college athletics as it is an important resource for student-athletes, especially for their success later in life. Likewise, there are currently no studies exploring athletic retirement from the perspective of student-athlete support or development services, a section of athletic departments that provides programming for the success of their student-athletes. Purpose: The purpose of this study was to explore the implications of athletic retirement from the perspective of directors and/or associate directors of student-athlete support or development services ...


Impacts Of Anthropogenic Noise On Litter Chemistry And Decomposition Processes In A Semi-Arid Ecosystem, Peggy Martinez Dec 2017

Impacts Of Anthropogenic Noise On Litter Chemistry And Decomposition Processes In A Semi-Arid Ecosystem, Peggy Martinez

Boise State University Theses and Dissertations

Chronic anthropogenic noise in ecosystems can change avian/arthropod/plant interactions, but it is unclear how changes in herbivory pressure affects functional traits of plants. We asked how anthropogenic noise, mediated through changes in arthropod abundance, altered timing of leaf senesce, chemical composition (i.e. C/N ratios, total phenolics) and decomposition rates of leaf litter in Wyoming big sagebrush (Artemisia tridentata spp. wyo.). Additionally, we asked if changes in arthropod abundance altered secondary metabolites (i.e. monoterpenes) in foliage. We broadcasted recorded gas compressor station noise (24hrs/day) from April through October 2015 in a sagebrush steppe ecosystem of ...


Development Of A Cholera Toxin Cta2/B Based Staphylococcus Aureus Vaccine To Prevent Bovine Mastitis, Neha Misra Dec 2017

Development Of A Cholera Toxin Cta2/B Based Staphylococcus Aureus Vaccine To Prevent Bovine Mastitis, Neha Misra

Boise State University Theses and Dissertations

Staphylococcus aureus is an important pathogen causing chronic and invasive disease worldwide. This bacterium is a leading cause of community and hospital acquired infections in humans, and is also known to infect wild and domestic animals. Bovine mastitis, or inflammation of the udder, is one of the most economically relevant diseases of the dairy industry, with a high incidence worldwide. S. aureus is a major etiological agent causing this disease. S. aureus mastitis is highly contagious and difficult or impossible to treat. Management practices at dairy farms, that include good sanitation and antibiotic use, have been partially successful in reducing ...


The Relative Importance Of Fire History, Management Treatments, Biotic, And Abiotic Factors On The Abundance Of Key Vegetative Components In An Endangered Sagebrush-Steppe Ecosystem, Ann Marie Raymondi Dec 2017

The Relative Importance Of Fire History, Management Treatments, Biotic, And Abiotic Factors On The Abundance Of Key Vegetative Components In An Endangered Sagebrush-Steppe Ecosystem, Ann Marie Raymondi

Boise State University Theses and Dissertations

Dryland ecosystems are globally distributed and occupy nearly half of Earth’s terrestrial surface. Drylands are particularly vulnerable to degradation and their restoration has become a global concern. Sagebrush-steppe ecosystems in the intermountain western United States have been subject to decades of active management efforts to address invasive species and restore plant communities, and can serve as a relevant case study to investigate dynamics between fire, invasive species, and management treatments in a representative dryland system. My objective was to determine the relative importance of fire history, management treatment history, abiotic, and biotic factors in relation to the abundance of ...


Acyl-Homoserine Lactone Based Modulators For Rhli, A Quorum Sensing Signal Synthase In Pseudomonas Aeruginosa, Daniel D. Shin Dec 2017

Acyl-Homoserine Lactone Based Modulators For Rhli, A Quorum Sensing Signal Synthase In Pseudomonas Aeruginosa, Daniel D. Shin

Boise State University Theses and Dissertations

Gram-negative bacteria use N-acyl-homoserine lactone (AHL) autoinducer based signal system, known as quorum sensing (QS), to modulate the gene expression for such traits as biofilm formation, toxin production, and antibiotic resistance. Therefore, there is great potential in pursuing quorum sensing inhibition (QSI) as a means of achieving antivirulence. Pseudomonas aeruginosa, an opportunistic pathogen commonly found in healthcare-related infections, use two LuxI/R type systems to regulate AHL-based quorum sensing: LasI/R and RhlI/R. LasI (initiator protein/signal synthase) and LasR (receptor) use 3-oxododecanoyl-L-homoserine lactone signal molecule while RhlI and RhlR use butanoyl-L-homoserine lactone autoinducer. Thus far, most of ...


Oncostatin M Promotes Breast Cancer Metastasis: Increased Expression Of Pro-Angiogenic Factors, Inflammatory Cytokine Expression, And Circulating Tumor Cell Numbers, Ken Tawara Dec 2017

Oncostatin M Promotes Breast Cancer Metastasis: Increased Expression Of Pro-Angiogenic Factors, Inflammatory Cytokine Expression, And Circulating Tumor Cell Numbers, Ken Tawara

Boise State University Theses and Dissertations

Breast cancer is the most diagnosed cancer type in women and its resultant mortality is second only to lung cancer worldwide. While breast cancer is known to have many risk factors, inflammation remains an unquantifiable risk, and it can arise from obesity, depression, poor health, autoimmune diseases, and other conditions that cause systemic chronic inflammation. Chronic inflammation is gaining recognition for its role in cancer development, the potentiation of a metastatic phenotype in cancer cells, and decreased survival in breast cancer patients. In particular, inflammatory cytokines in the interleukin-6 (IL-6) family have been shown to promote an epithelial-mesenchymal transition (EMT ...


The Cost Of Roaming Free: Assessing The Effects Of Plant Secondary Metabolites On Diet Selection And Nutritional Condition In A Free-Ranging Generalist Herbivore, Daniel Patrick Melody Dec 2017

The Cost Of Roaming Free: Assessing The Effects Of Plant Secondary Metabolites On Diet Selection And Nutritional Condition In A Free-Ranging Generalist Herbivore, Daniel Patrick Melody

Boise State University Theses and Dissertations

Large vertebrate herbivores have a wide variety of browsing options available. However, most plants contain a suite of plant secondary metabolites (PSMs) that can have toxic effects when ingested. Herbivores must therefore make dietary choices that minimize the potentially harmful effects of PSM ingestion and maximize the use of available nutrients and protein. During winter months, in northern latitudes, climatological factors restrict browsing options and many populations of herbivores must subsist primarily on forage that is relatively poor in nutritional quality and high in PSMs. Many species of herbivores have developed a suite of behavioral and physiological adaptations to cope ...


Acute Effects Of The Training Mask On Short-Term Recovery During Rowing Intervals, Hayden W. Hess Dec 2017

Acute Effects Of The Training Mask On Short-Term Recovery During Rowing Intervals, Hayden W. Hess

Boise State University Theses and Dissertations

The purpose of this study was to examine the acute effects of the Training Mask 2.0 (TM) on performance (m), blood lactate, heart rate recovery (HRR), stroke volume (SV), cardiac output (Q̇), heart rate variability (HRV), and breath rate recovery (BRR) when used during short-term recovery. Methods: Seven trained males completed two interval training conditions (TM and Sham TM). Each condition consisted of five, 1-min, max effort rows with 3-min recoveries. The TM (or Sham TM) was worn during each 3-min recovery. A repeated measures 2x5 (condition x interval) ANOVA was used to determine significant main effects for condition ...


Oral Creatine Hydrochloride Supplementation: Acute Effects On Submaximal, Intermittent Bouts Of Bench Press And Vertical Jump Exercises, Daniel Mcdonough Dec 2017

Oral Creatine Hydrochloride Supplementation: Acute Effects On Submaximal, Intermittent Bouts Of Bench Press And Vertical Jump Exercises, Daniel Mcdonough

Boise State University Theses and Dissertations

The purpose of this study was to examine the acute effects of oral creatine hydrochloride (CrHCl) supplementation on three repeated bouts of bench press and vertical jumping exercises and body composition measures (body weight (BW), fat-free mass (FFM) and fat mass (FM)). Methods: Fifteen resistance trained males completed 3 sets of the barbell bench press (70% 1RM) and 3 sets of the repeated counter-movement vertical jump (CMJ; 85% maximal CMJ height), with 2 min rest between sets, before and after a 7 d CrHCl intervention (4 g·day-1). A two-factor repeated measures ANOVA was used to determine significant main ...


The Role Of Disease And Ectoparasites In The Ecology Of Nestling Golden Eagles, Benjamin Michael Dudek Aug 2017

The Role Of Disease And Ectoparasites In The Ecology Of Nestling Golden Eagles, Benjamin Michael Dudek

Boise State University Theses and Dissertations

Climate and anthropogenic land use changes can alter biological communities and affect disease infection rates and parasite species distribution and abundance. Management to mitigate the threats of emerging infectious diseases and parasite species requires identifying and understanding factors that influence individual susceptibility within populations. Golden eagles (Aquila chrysaetos) in southwestern Idaho face several current and emerging threats, including a landscape-mediated diet shift that has increased the potential for disease infection, and warming temperatures that may increase the distribution and abundance of hematophagous ectoparasites. We examined prevalence of Trichomonas gallinae infection in golden eagle nestlings across western North America in 2015 ...


The Evolution Of Anti-Bat Sensory Illusions In Moths, Juliette Rubin Aug 2017

The Evolution Of Anti-Bat Sensory Illusions In Moths, Juliette Rubin

Boise State University Theses and Dissertations

Prey-generated illusions span sensory systems. Previous studies have mainly focused on visual illusions presented by prey coloring or morphology, but few have explored illusions produced via sound. We investigate an acoustic sensory illusion in moths, created by complex hindwing structures that divert echolocating bat predators. A phylogeny of the moth family, Saturniidae, in combination with data from geometric morphometrics, reveals that hindwings have repeatedly elongated to form tails across evolutionary time. Using high-speed, multi-camera, synchronized videos of bat-moth battles, we quantified the selective pressure of predation on extant and experimentally-modified moths, defined by moth escape success from bat attack. We ...


Landscape-Scale Manipulation Of The Acoustic Environment Alters The Distribution Of Breeding Birds And Arthropods, Elizeth Cinto-Mejia Aug 2017

Landscape-Scale Manipulation Of The Acoustic Environment Alters The Distribution Of Breeding Birds And Arthropods, Elizeth Cinto-Mejia

Boise State University Theses and Dissertations

Oil and gas development has rapidly increased across the world over the last several decades. Anthropogenic noise, an invisible pollutant that alters animal distribution and behavior, could be responsible for documented wildlife population declines near loud compressor stations in energy extraction fields. We experimentally played back compressor noise, creating a “phantom natural gas field” in a large-scale experiment, and tested the effects of noise on songbird distributions during the breeding season and on arthropod distributions. Further, to begin to understand the influence of noise produced by different types of extraction infrastructure, we examined the effects of sound intensity and bandwidth ...


Lysenin Channels As Single Molecule Nano-Sensors And Nano-Switches For Controlled Membrane Permeability, Nisha Shrestha Aug 2017

Lysenin Channels As Single Molecule Nano-Sensors And Nano-Switches For Controlled Membrane Permeability, Nisha Shrestha

Boise State University Theses and Dissertations

Pore-forming toxins secreted by various evolutionarily distant organisms are important components of their innate defense mechanisms. These toxins may kill the target cells by inserting un-regulated channels into the plasma membrane. Tampering with the otherwise well-controlled membrane permeability alters cell homeostasis by contributing to un-controlled dissipation of both chemical and electrical gradients, which is often an essential component of virulence mechanisms leading to cell death. However, the same ability to create nanoscopic conducting pathways, i.e. nanopores, has been exploited for creating powerful tools in nano-biotechnology. Single nano-channels reconstituted in artificial planar lipid membranes are extremely versatile sensors that are ...