Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

PDF

Theses/Dissertations

Food Science

Androgen receptor

Publication Year

Articles 1 - 2 of 2

Full-Text Articles in Life Sciences

Exposure To Dietary Selenium And Soy Isoflavones In Utero Provides Greater Protection Against Prostate Cancer Risk Factors In Tramp Mice Than Exposure Beginning At 6 Weeks, Heather Schofield Lindsay Jun 2012

Exposure To Dietary Selenium And Soy Isoflavones In Utero Provides Greater Protection Against Prostate Cancer Risk Factors In Tramp Mice Than Exposure Beginning At 6 Weeks, Heather Schofield Lindsay

Theses and Dissertations

Prostate cancer is the second most commonly occurring cancer in men in the United States. Generally, an extended period of time is needed for a mutation to develop into a full scale tumor. Because of this long latency period, lifestyle and environmental factors, such as diet, may play an important role in the development and progression of the disease. Diet is one factor that has been implicated in the risk for developing prostate cancer. We previously showed that diets high in soy isoflavones and selenium (Se) decreased androgen receptor expression and expression of androgen regulated genes in healthy rat prostates ...


Chemopreventive Effects Of Dietary Selenium And Soy Isoflavones In A Mouse Model Of Prostate Cancer, Trevor Elisha Quiner Jun 2010

Chemopreventive Effects Of Dietary Selenium And Soy Isoflavones In A Mouse Model Of Prostate Cancer, Trevor Elisha Quiner

Theses and Dissertations

Prostate cancer is the most commonly diagnosed non-skin cancer in men and the second leading cause of cancer death in the United States. Prostate cancer, like many cancers, is a disease that generally requires a long period of time to develop and grow before it becomes detectable. This long period of latency makes prostate cancer a candidate for dietary chemoprevention. Soy and selenium (Se), are associated with a decreased risk of prostate cancer. We previously showed that high dietary intake of selenium (Se) and soy isoflavones decreased the expression of the androgen receptor (AR) and AR-regulated genes in the prostates ...