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Full-Text Articles in Life Sciences

Stunting And Infectious Disease In Ethiopian And Zambian Children, Alyssa Arndt Apr 2020

Stunting And Infectious Disease In Ethiopian And Zambian Children, Alyssa Arndt

NUTR/GLST 498b: Global Research Experiences in Nutrition & Health

PURPOSE: To evaluate whether children who are malnourished/stunted are more likely to have experienced infectious disease.

METHODS: 6th and 7th students (n=546) were interviewed about health history and assessed using anthropometry.

RESULTS: Children who are short for their age also have higher rates of stunting. Malaria is the most experienced infectious disease.

CONCLUSIONS: Given that malaria was the most common infectious disease experience listed among middle school children, and that those who have experienced disease are more likely to be stunted, increased malaria prevention methods may improve the long-term health of Ethiopian and Zambian schoolchildren.


Association Between Sulfur-Metabolizing Bacterial Communities In Stool And Risk Of Distal Colorectal Cancer In Men, Long H. Nguyen, Wenjie Ma, Dong D. Wang, Yin Cao, Himel Mallick, Teklu K. Gerbaba, Jason Lloyd-Price, Galeb Abu-Ali, A. Brantley Hall, Daniel Sikavi, David A. Drew, Raaj S. Mehta, Cesar Arze, Amit D. Joshi, Yan Yan, Tobyn Branck, Casey Dulong, Kerry L. Ivey, Shuji Ogino, Eric B. Rimm, Mingyang Song, Wendy S. Garrett, Jacques Izard, Cutis Huttenhower, Andrew T. Chan Apr 2020

Association Between Sulfur-Metabolizing Bacterial Communities In Stool And Risk Of Distal Colorectal Cancer In Men, Long H. Nguyen, Wenjie Ma, Dong D. Wang, Yin Cao, Himel Mallick, Teklu K. Gerbaba, Jason Lloyd-Price, Galeb Abu-Ali, A. Brantley Hall, Daniel Sikavi, David A. Drew, Raaj S. Mehta, Cesar Arze, Amit D. Joshi, Yan Yan, Tobyn Branck, Casey Dulong, Kerry L. Ivey, Shuji Ogino, Eric B. Rimm, Mingyang Song, Wendy S. Garrett, Jacques Izard, Cutis Huttenhower, Andrew T. Chan

Faculty Publications in Food Science and Technology

Background & Aims: Sulfur-metabolizing microbes, which convert dietary sources of sulfur into genotoxic hydrogen sulfide (H2S), have been associated with development of colorectal cancer (CRC). We identified a dietary pattern associated with sulfur-metabolizing bacteria in stool and then investigated its association with risk of incident CRC using data from a large prospective study of men.

Methods: We collected data from 51,529 men enrolled in the Health Professionals Follow-up Study since 1986 to determine the association between sulfur-metabolizing bacteria in stool and risk of CRC over 26 years of follow-up. First, in a subcohort of 307 healthy men, we profiled serial stool metagenomes and metatranscriptomes and assessed diet using semiquantitative food frequency questionnaires to identify food groups associated with 43 bacterial species involved in sulfur metabolism. We used these data to develop a sulfur microbial dietary score. We then used Cox proportional hazards modeling to evaluate adherence to this pattern among eligible individuals (n = 48,246) from 1986 through 2012 with risk for incident CRC.

Results: Foods associated with higher sulfur microbial diet scores included increased consumption of processed meats and low-calorie drinks and lower consumption of vegetables and legumes. Increased sulfur microbial diet scores were associated with risk of distal colon and rectal cancers, after adjusting for other risk factors (multivariable relative risk, highest vs lowest quartile, 1.43; 95% confidence interval 1.14–1.81; P-trend = .002). In contrast, sulfur microbial diet scores were not associated with risk of proximal colon cancer (multivariable relative risk 0.86; 95% CI 0.65–1.14; P-trend = .31).

Conclusions: In an analysis of participants in the Health Professionals Follow-up Study, we found that long-term adherence to a dietary pattern associated with sulfur-metabolizing bacteria in stool was associated with an increased risk of distal CRC. Further studies are needed to determine how sulfur-metabolizing bacteria might contribute to CRC pathogenesis.


De Novo Sequencing And Analysis Of Salvia Hispanica Tissue-Specific Transcriptome And Identification Of Genes Involved In Terpenoid Biosynthesis, James Wimberley, Joseph Cahill, Hagop S. Atamian Mar 2020

De Novo Sequencing And Analysis Of Salvia Hispanica Tissue-Specific Transcriptome And Identification Of Genes Involved In Terpenoid Biosynthesis, James Wimberley, Joseph Cahill, Hagop S. Atamian

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Salvia hispanica (commonly known as chia) is gaining popularity worldwide as a healthy food supplement due to its low saturated fatty acid and high polyunsaturated fatty acid content, in addition to being rich in protein, fiber, and antioxidants. Chia leaves contain plethora of secondary metabolites with medicinal properties. In this study, we sequenced chia leaf and root transcriptomes using the Illumina platform. The short reads were assembled into contigs using the Trinity software and annotated against the Uniprot database. The reads were de novo assembled into 103,367 contigs, which represented 92.8% transcriptome completeness and a diverse set of ...


Donating Safe And Wholesome Food, Brian Nummer, Paula Scott Mar 2020

Donating Safe And Wholesome Food, Brian Nummer, Paula Scott

All Current Publications

Americans dispose of millions of pounds of tons of food, and the U.S. Department of Agriculture estimates that 11.8 percent of American households, or about 15 million, had difficulty providing enough food for all their family members (Coleman-Jensen et al., 2018). Much of the food disposed into landfills is wholesome and edible. This fact sheet outlines how a potential food donor can get started and get food into the hands of the needy.


Scaling Human Fiber Intakes For Mouse Microbiome Studies, Robert E. Ward Mar 2020

Scaling Human Fiber Intakes For Mouse Microbiome Studies, Robert E. Ward

Funded Research Records

No abstract provided.


Serum Vitamin B12, And Related Mtrr And Cubilin Genotypes, Predict Neural Outcomes Across The Ad Spectrum, K. E. Mcliman, A. D. Collazo Martinez, Jonathan P. Mochel, Karin D. Allenspach, Auriel A. Willette Mar 2020

Serum Vitamin B12, And Related Mtrr And Cubilin Genotypes, Predict Neural Outcomes Across The Ad Spectrum, K. E. Mcliman, A. D. Collazo Martinez, Jonathan P. Mochel, Karin D. Allenspach, Auriel A. Willette

Biomedical Sciences Publications

Epidemiological studies show mixed findings for serum vitamin B12 and both cognitive and regional volume outcomes. No studies to date have comprehensively examined, in non-supplemented individuals, serum B12 level associations with neurodegeneration, hypometabolism, and cognition across the Alzheimer's disease (AD) spectrum. Serum vitamin B12 was assayed from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL). Voxel-wise analyses regressed B12 levels against regional gray matter (GM) volume and glucose metabolism (p


Exploring Attitudes And Reactions To Unfamiliar Food Pairings: An Examination Of The Underlying Motivations And The Impact Of Culinary Education, Mark Traynor, Andrew Moreo, Lisa Cain, Roisin Burke, Catherine Barry-Ryan Feb 2020

Exploring Attitudes And Reactions To Unfamiliar Food Pairings: An Examination Of The Underlying Motivations And The Impact Of Culinary Education, Mark Traynor, Andrew Moreo, Lisa Cain, Roisin Burke, Catherine Barry-Ryan

Articles

A mixed-methodology study was conducted to better understand consumer attitudes and behaviors toward novel food pairings and the impact of culinary education. Focus groups were conducted to investigate the underlying motivational factors to the reactions and behaviors toward unfamiliar foods. The second phase of the study consisted of sensory evaluation by two separate cohorts, panelists with and without culinary education, of food products created through the novel pairings of foods. Panelists with culinary education expressed a greater overall liking for the animal-based pairing. Sensory-Affective and Ideational factors appeared to be underlying motivational factors of these hedonic reactions.


Growing Torula Yeast (Candida Utilis) For Food Grade Fatty Acids, Zachary Christman Feb 2020

Growing Torula Yeast (Candida Utilis) For Food Grade Fatty Acids, Zachary Christman

Theses, Dissertations, and Student Research in Agronomy and Horticulture

The focus of this article is the cultivation of a food grade yeast for the production of fatty acids without the restrictions of climate or growing season. Torula yeast (Candida utilis) was selected since it can grow on a wide variety of culture media and has over 60 years of use in the food industry. The fatty acid composition of Candida utilis grown on two different media are presented in this article; the first example using completely synthetic media and another using distiller’s vinasse. Also, the effect of different culturing conditions on the percentage of various fatty acids will ...


Potential Use Of Biotherapeutic Bacteria To Target Colorectal Cancer-Associated Taxa, Gareth Lawrence, Maire Begley, Paul D. Cotter, Caitríona M. Guinane Jan 2020

Potential Use Of Biotherapeutic Bacteria To Target Colorectal Cancer-Associated Taxa, Gareth Lawrence, Maire Begley, Paul D. Cotter, Caitríona M. Guinane

Dept. of Biological Sciences Articles

The role of the gut microbiome in human health and disease is the focus of much attention. It has been widely agreed upon that our gut bacteria play a role in host immunity, nutrient absorption, digestion, metabolism, and other key drivers of health. Furthermore, certain microbial signatures and specific taxa have also been associated with the development of diseases, such as obesity; inflammatory bowel disease; and, indeed, colorectal cancer (CRC), which is the focus of this review. By extension, such taxa represent potential therapeutic targets. In particular, the emerging human pathogen Fusobacterium nucleatum represents an important agent in CRC development ...


Metformin Uptake And Translocation In Chickpeas: Determination Using Liquid Chromatography−Mass Spectrometry, Brett Nespor, Anastasia Andrianova, Sean Pollack, Creighton Pfau, Muhammad Arifuzzaman, Nazrul Islam, Alena Kubatova, Khwaja Hossain Jan 2020

Metformin Uptake And Translocation In Chickpeas: Determination Using Liquid Chromatography−Mass Spectrometry, Brett Nespor, Anastasia Andrianova, Sean Pollack, Creighton Pfau, Muhammad Arifuzzaman, Nazrul Islam, Alena Kubatova, Khwaja Hossain

Chemistry Faculty Publications

Multiple chronic conditions (MCCs) such as diabetes, hypertension, heart disease, arthritis, asthma, and common respiratory problems are prevalent in over one-fourth of Americans, and separate drugs are prescribed to manage each of the diseases. The nutritive crop seeds loaded with multiple drugs could be a cheap and sustainable alternative to drugs produced by pharmaceutical companies. Our long-term goal is to produce chickpea seeds containing comparable dosages of multiple drugs regularly prescribed for managing MCC. In this work, we conducted experiments to understand the uptake and translocation of metformin into the tissues of chickpea to demonstrate the applicability of LC–HR-ToF-MS ...


Antiproliferative And Apoptotic Effects Of Proteins From Black Seeds (Nigella Sativa) On Human Breast Mcf-7 Cancer Cell Line, Yamna Khursid, Basir Syed, Shabana U. Simjee, Obaid Beg, Aftab Ahmed Jan 2020

Antiproliferative And Apoptotic Effects Of Proteins From Black Seeds (Nigella Sativa) On Human Breast Mcf-7 Cancer Cell Line, Yamna Khursid, Basir Syed, Shabana U. Simjee, Obaid Beg, Aftab Ahmed

Pharmacy Faculty Articles and Research

Background

Nigella sativa (NS), a member of family Ranunculaceae is commonly known as black seed or kalonji. It has been well studied for its therapeutic role in various diseases, particularly cancer. Literature is full of bioactive compounds from NS seed. However, fewer studies have been reported on the pharmacological activity of proteins. The current study was designed to evaluate the anticancer property of NS seed proteins on the MCF-7 cell line.

Methods

NS seed extract was prepared in phosphate-buffered saline (PBS), and proteins were precipitated using 80% ammonium sulfate. The crude seed proteins were partially purified using gel filtration chromatography ...


Cost Assessment Of Five Different Maize Grain Handling Techniques To Reduce Postharvest Losses From Insect Contamination, Bernard Darfour, Kurt A. Rosentrater Jan 2020

Cost Assessment Of Five Different Maize Grain Handling Techniques To Reduce Postharvest Losses From Insect Contamination, Bernard Darfour, Kurt A. Rosentrater

Agricultural and Biosystems Engineering Publications

Farmers in developing nations encounter high postharvest losses mainly attributable to the lack of modern techniques for threshing, cleaning, grading, and grain storage. Mechanized handling of grain in developing countries is rare, although the technology is effective against insects and pest infestations. The objective was to evaluate the cost-effectiveness of five grain handling techniques that have the ability to reduce postharvest losses from insect infestation. The five methods were metal silo plus all accessories (m. silo + acc.), metal silo only (m. silo), woven polypropylene plus phosphine (w. PP. + Phos.), woven polypropylene only (w. PP.), and Purdue Improved Crop Storage bags ...


Epidemiology, Detection, And Intervention/Control Of Cyclospora Cayetanensis: A Scoping Review Protocol, Sarah C. Totton, Annette M. O'Connor, Mary E. Torrence, Jan M. Sargeant Jan 2020

Epidemiology, Detection, And Intervention/Control Of Cyclospora Cayetanensis: A Scoping Review Protocol, Sarah C. Totton, Annette M. O'Connor, Mary E. Torrence, Jan M. Sargeant

Veterinary Diagnostic and Production Animal Medicine Reports

Background: Cyclosporiasis is a food- and waterborne illness in humans caused by the consumption of contaminated food or water. As the causative agent, Cyclospora cayetanensis, has only been recently described, the published literature is limited and no scoping reviews on this topic have yet been conducted.

Objectives: Our objective is to conduct a scoping review of the epidemiology, detection in matrix, and intervention/control of C. cayetanensis worldwide in humans, plant-based food, and in the environment with the aim of identifying gaps in the literature, potential areas where there may be sufficient literature to warrant a systematic review, and prioritizing ...


Jackrabbit Dairy & Food Review, Winter 2019-2020, Vikram V. Mistry Jan 2020

Jackrabbit Dairy & Food Review, Winter 2019-2020, Vikram V. Mistry

The Jackrabbit Dairy & Food Review

This is the Winter 2019- 2020 Jackrabbit Dairy and Food Review.
It contains the following articles and information: Message from the Department Head, David A. Thompson Endowment, New Personnel, Judging Activities, Dairy Club, Student Accomplishments, Food Science Club, Career Opportunities, Professional Activities of Faculty and Staff, Dairy Facilities, 2019 Graduates, Where Are They Now?, Scholarships, Dairy and Food Science Students, Outreach, Distinguished Alumnus


Dental Health Factors Among Primary School Children In Southern Regions Of Ethiopia And Zambia, Gisselle Hernandez Jan 2020

Dental Health Factors Among Primary School Children In Southern Regions Of Ethiopia And Zambia, Gisselle Hernandez

NUTR/GLST 498b: Global Research Experiences in Nutrition & Health

Purpose: Assess oral health status, and factors affecting oral health, among primary schoolchildren in southern Ethiopia and Zambia. Methods: Visual dental assessments, anthropometric measurements, and questionnaires used to collect data among 6th and 7th grade students. Results: Although stunting rates were nearly equal, decay rates were not; 17.51% of Zambian students and 47.27% of Ethiopian students had one or more decayed teeth. Ethiopian students with dental fluorosis (74.55%) had higher rates of decay than those without the condition (p < .05). There were also significant differences between Ethiopians and Zambians regarding use of dental hygiene tools: Ethiopians were more likely to use dental sticks, while Zambians employed toothbrushes for cleaning. Conclusions: Dental health and hygiene education, focused on unique socioecological settings, could improve the oral health status of Ethiopian and Zambian children.

PowerPoint file attached below


Marine Toxins Targeting Kv1 Channels: Pharmacological Tools And Therapeutic Scaffolds, Rocio K. Finol-Urdaneta, Aleksandra Belovanovic, Milica Micic-Vicovac, Gemma K. Kinsella, Jeffrey R. Mcarthur, Ahmed Al-Sabi Jan 2020

Marine Toxins Targeting Kv1 Channels: Pharmacological Tools And Therapeutic Scaffolds, Rocio K. Finol-Urdaneta, Aleksandra Belovanovic, Milica Micic-Vicovac, Gemma K. Kinsella, Jeffrey R. Mcarthur, Ahmed Al-Sabi

Articles

Toxins from marine animals provide molecular tools for the study of many ion channels, including mammalian voltage-gated potassium channels of the Kv1 family. Selectivity profiling and molecular investigation of these toxins have contributed to the development of novel drug leads with therapeutic potential for the treatment of ion channel-related diseases or channelopathies. Here, we review specific peptide and small-molecule marine toxins modulating Kv1 channels and thus cover recent findings of bioactives found in the venoms of marine Gastropod (cone snails), Cnidarian (sea anemones), and small compounds from cyanobacteria. Furthermore, we discuss pivotal advancements at exploiting the interaction of κM-conotoxin RIIIJ ...


Antimicrobial Peptide Identification Using Multi-Scale Convolutional Network, Xin Su, Jing Xu, Yanbin Yin, Xiongwen Quan, Han Zhang Dec 2019

Antimicrobial Peptide Identification Using Multi-Scale Convolutional Network, Xin Su, Jing Xu, Yanbin Yin, Xiongwen Quan, Han Zhang

Faculty Publications in Food Science and Technology

Background: Antibiotic resistance has become an increasingly serious problem in the past decades. As an alternative choice, antimicrobial peptides (AMPs) have attracted lots of attention. To identify new AMPs, machine learning methods have been commonly used. More recently, some deep learning methods have also been applied to this problem.

Results: In this paper, we designed a deep learning model to identify AMP sequences. We employed the embedding layer and the multi-scale convolutional network in our model. The multi-scale convolutional network, which contains multiple convolutional layers of varying filter lengths, could utilize all latent features captured by the multiple convolutional layers ...


Antioxidant Activity Of Sesame Seed Lignans In Sunflower And Flaxseed Oils, S. Y. Hadeel, S. A. Khalida, Marie K. Walsh Dec 2019

Antioxidant Activity Of Sesame Seed Lignans In Sunflower And Flaxseed Oils, S. Y. Hadeel, S. A. Khalida, Marie K. Walsh

Nutrition, Dietetics, and Food Sciences Faculty Publications

This study investigated the antioxidant activity of crude lignan extracts and purified lignans (sesamin, sesamolin, and sesamol) in sunflower and flaxseed oils. Lignan extracts were prepared from roasted sesame seed oil (LRSO) and unroasted sesame seed oil (LUSO). Additionally, the individual lignans were purified from both oils. The crude extracts and purified lignans were added at concentrations of 0.01, 0.02 and 0.03% to the oils and stored at 25 and 65°C over time and peroxide values and thiobarbituric acid values were measured. Each oil showed an increase in oxidation over time, with the samples stored at ...


Effect Of High-Power Sonication Pretreatment On Extraction And Some Physicochemical Properties Of Proteins From Chickpea, Kidney Bean, And Soybean, Bibek Byanju, Md Mahfuzur Rahman, Milagros P. Hojilla-Evangelista, Buddhi P. Lamsal Dec 2019

Effect Of High-Power Sonication Pretreatment On Extraction And Some Physicochemical Properties Of Proteins From Chickpea, Kidney Bean, And Soybean, Bibek Byanju, Md Mahfuzur Rahman, Milagros P. Hojilla-Evangelista, Buddhi P. Lamsal

Food Science and Human Nutrition Publications

Impact of high-power sonication (HPS) as pretreatment in extraction and some physicochemical properties of proteins from soybean flakes, flour of soybean, chickpea, and kidney bean was evaluated. Soybean flakes and flours from soybean, chickpea, and kidney bean were dispersed in distilled water (1.10 w/v) and sonicated at two power densities (PD) of 2.5 and 4.5 W/cm3 for 5 min continuously. Proteins were extracted at pH range 8–8.5. PD 2.5 and 4.5 W/cm3 significantly increased protein extraction yields from soy flakes to 29.03% and 25.87%, respectively, compared to 15 ...


A Novel And Green Nanoparticle Formation Approach To Forming Low-Crystallinity Curcumin Nanoparticles To Improve Curcumin’S Bioaccessibility, Ali Ubeyitogullari, Ozan Ciftci Dec 2019

A Novel And Green Nanoparticle Formation Approach To Forming Low-Crystallinity Curcumin Nanoparticles To Improve Curcumin’S Bioaccessibility, Ali Ubeyitogullari, Ozan Ciftci

Faculty Publications in Food Science and Technology

Health-promoting effects of curcumin are well-known; however, curcumin has a very low bioavailability due to its crystalline structure. The main objective of this study was to develop a novel green nanoparticle formation method to generate low-crystallinity curcumin nanoparticles to enhance the bioavailability of curcumin. Nanoporous starch aerogels (NSAs) (surface area of 60 m2/g, pore size of 20 nm, density of 0.11 g/cm3, and porosity of 93%) were employed as a mold to produce curcumin nanoparticles with the help of supercritical carbon dioxide (SC-CO2). The average particle size of the curcumin nanoparticles was 66 nm. Impregnation into NSAs ...


The Anti-Campylobacter Activity And Mechanisms Of Pinocembrin Action, Anja Klančnik, Katarina Šimunović, Jasna Kovac, Orhan Sahin, Zuowei Wu, Darinka Vučković, Maja Abram, Qijing Zhang, Sonja Smole Možina Dec 2019

The Anti-Campylobacter Activity And Mechanisms Of Pinocembrin Action, Anja Klančnik, Katarina Šimunović, Jasna Kovac, Orhan Sahin, Zuowei Wu, Darinka Vučković, Maja Abram, Qijing Zhang, Sonja Smole Možina

Veterinary Diagnostic and Production Animal Medicine Publications

We investigated the anti-Campylobacter activity of pinocembrin and its mechanism of action, as well as Campylobacter responses to pinocembrin treatment at the genetic and phenotypic levels, using C. jejuni NCTC 11168 and a multidrug efflux system repressor mutant (11168ΔcmeR). At its minimal inhibitory concentration, pinocembrin significantly increased cell membrane permeability of Campylobacter. Interestingly, at sub-inhibitory concentrations, pinocembrin did not significantly alter membrane functionality and it increased bacterial fitness. Treatment with pinocembrin evoked decreased expression of ribosomal proteins and down-regulation of several NADH dehydrogenase I chain subunits and proteins involved in iron uptake. This suggests altered protein production and redox cycle ...


Evaluating The Efficacy Of Whole Cooked Enriched Egg In Modulating Health-Beneficial Biological Activities, Emerson Nolasco Dec 2019

Evaluating The Efficacy Of Whole Cooked Enriched Egg In Modulating Health-Beneficial Biological Activities, Emerson Nolasco

Dissertations, Theses, & Student Research in Food Science and Technology

The whole egg is known as nutritious food in the human diet with a wide reach due to its accessibility. It’s highly bioavailable proteins and dietary compounds, and their health-beneficial properties make the egg a potential functional food. Still, little is known about how the production and processing methods can modulate its potential health-beneficial properties. To attend the knowledge gaps, the study established objectives look to evaluate the effect of the hen breed, egg enrichment, and cooking methods. The hen breed and egg enrichment maintained overall the egg quality. Confirming the capacity of the egg industry of improving the ...


Systematic Reviews And Meta-Analyses In Animal Health, Performance, And On-Farm Food Safety: A Scoping Review, Rachael Vriezen, Jan M. Sargeant, Ellen Vriezen, Mark Reist, Charlotte B. Winder, Annette M. O’Connor Dec 2019

Systematic Reviews And Meta-Analyses In Animal Health, Performance, And On-Farm Food Safety: A Scoping Review, Rachael Vriezen, Jan M. Sargeant, Ellen Vriezen, Mark Reist, Charlotte B. Winder, Annette M. O’Connor

Veterinary Diagnostic and Production Animal Medicine Publications

Systematic reviews and meta-analyses are used to summarize and interpret evidence for clinical decision-making in human health. The extent of the application of these methods in veterinary medicine and animal agriculture is unknown. The goal of this scoping study was to ascertain trends in the publication of systematic reviews and meta-analyses examining animal health, animal performance, and on-farm food safety. Online databases were searched for reviews published between 1993 and 2018 that focused on relevant outcomes in domestic livestock, companion animals, or wildlife species. In total 1787 titles and abstracts underwent data characterization. Dairy cattle, fish, and pigs were the ...


Keeping Allergen Names Clear And Defined, Sanny K. Chan, Anna Pomés, Christiane Hilger, Janet M. Davies, Geoffrey Mueller, Annette Kuehn, Andreas L. Lopata, Gabriele Gadermaier, Marianne Van Hage, Monika Raulf, Richard E. Goodman Nov 2019

Keeping Allergen Names Clear And Defined, Sanny K. Chan, Anna Pomés, Christiane Hilger, Janet M. Davies, Geoffrey Mueller, Annette Kuehn, Andreas L. Lopata, Gabriele Gadermaier, Marianne Van Hage, Monika Raulf, Richard E. Goodman

Faculty Publications in Food Science and Technology

The World Health Organization/International Union of Immunological Societies (WHO/IUIS) Allergen Nomenclature Sub-Committee was established in 1986 by leading allergists to standardize names given to proteins that cause IgE-mediated reactions in humans. The Sub-Committee’s objective is to assign unique names to allergens based on a critical analysis of confidentially submitted biochemical and clinical data from researchers, often prior to publication to preserve consistency. The Sub-Committee maintains and revises the database as the understanding of allergens evolves. This report summarizes recent developments that led to updates in classification of cockroach group 1 and 5 allergens to animal as well ...


Gene Expression Value Prediction Based On Xgboost Algorithm, Wei Li, Yanbin Yin, Xiongwen Quan, Han Zhang Nov 2019

Gene Expression Value Prediction Based On Xgboost Algorithm, Wei Li, Yanbin Yin, Xiongwen Quan, Han Zhang

Faculty Publications in Food Science and Technology

Gene expression profiling has been widely used to characterize cell status to reflect the health of the body, to diagnose genetic diseases, etc. In recent years, although the cost of genome-wide expression profiling is gradually decreasing, the cost of collecting expression profiles for thousands of genes is still very high. Considering gene expressions are usually highly correlated in humans, the expression values of the remaining target genes can be predicted by analyzing the values of 943 landmark genes. Hence, we designed an algorithm for predicting gene expression values based on XGBoost, which integrates multiple tree models and has stronger interpretability ...


Prophylactic Effects Of Isomaltodextrin In A Balb/C Mouse Model Of Egg Allergy, Yoshinori Mine, Yan Jin, Hua Zhang, Prithy Rupa, Kaustav Majumder, Takeo Sakurai, Yoshifumi Taniguchi, Ryodai Takagaki, Hikaru Watanabe, Hitoshi Mitsuzumi Nov 2019

Prophylactic Effects Of Isomaltodextrin In A Balb/C Mouse Model Of Egg Allergy, Yoshinori Mine, Yan Jin, Hua Zhang, Prithy Rupa, Kaustav Majumder, Takeo Sakurai, Yoshifumi Taniguchi, Ryodai Takagaki, Hikaru Watanabe, Hitoshi Mitsuzumi

Faculty Publications in Food Science and Technology

The aim of this study was to evaluate the potential effects of isomaltodextrin (IMD), a dietary saccharide polymer derived from enzymatically produced from starch, on the ability to alter immune response (IR) bias to hen egg ovalbumin (Ova) induced allergic inflammation in mice. Groups of Balb/c mice were pre-treated with various doses of IMD in drinking water (1.0, 2.5, and 5.0% w/v) for 6 weeks and subsequently sensitized to the Ova together with continuous administration of IMD. To evaluate changes in immune response bias, immunoglobulin isotype-associated antibody activity, concentrations of type 1 and 2 cytokines ...


Effect Of Processing On Microbiota Accessible Carbohydrates In Whole Grains, Caroline Smith Nov 2019

Effect Of Processing On Microbiota Accessible Carbohydrates In Whole Grains, Caroline Smith

Dissertations, Theses, & Student Research in Food Science and Technology

There is potential to increase microbiota accessible carbohydrates (MAC) in whole grains through food processing. Therefore, different processing conditions for boiling and extrusion of whole wheat flour were studied for their effect on MAC. Processing conditions had a minimal effect on fermentation response using 2 fecal samples of disparate composition. However, the processing method had an impact on the fermentation of non-digestible carbohydrates and subsequent short chain fatty acids production, but only for a microbiome with high diversity and a predominance of microbes associated with dietary fiber intake. Subsequently, five processing methods: boiling, extrusion, unleavened bread, yeast bread, and sourdough ...


The Integration Of Blockchain Technology To The Beef Industry – A Comparative Analysis, Cole N. Hancock Oct 2019

The Integration Of Blockchain Technology To The Beef Industry – A Comparative Analysis, Cole N. Hancock

Social Impact Research Experience (SIRE)

This paper seeks to explore the different plausible and implemented applications of blockchain technology in the beef industry in two representative markets: The United States and Kenya. Previous papers discuss implementation of blockchain to the beef industry, without a focus on the variations between beef industries and supply chains in various countries, a gap this paper aims to address. The main method of research has been primary, traveling to these countries and engaging in conversations with various stakeholders about their industry’s supply chain and the problems and opportunities therein. Overall this paper finds that the integration of blockchain to ...


The Effect Of Rapid Chilling Of Pork Carcasses During The Early Postmortem Period On Fresh Pork Quality, Aaron Blakely, Kenneth J. Prusa, Christine A. Fedler, Grant B. Sherrard, Edward M. Steadham, Kenneth J. Stalder, Carol L. Lorenzen, Elisabeth Huff-Lonergan, Steven M. Lonergan Oct 2019

The Effect Of Rapid Chilling Of Pork Carcasses During The Early Postmortem Period On Fresh Pork Quality, Aaron Blakely, Kenneth J. Prusa, Christine A. Fedler, Grant B. Sherrard, Edward M. Steadham, Kenneth J. Stalder, Carol L. Lorenzen, Elisabeth Huff-Lonergan, Steven M. Lonergan

Animal Science Publications

The objective was to investigate the effects of blast chilling on pork quality in cuts from the Longissimus thoracic et lumborum (LM), Psoas major (PM), Semimembranosus (SM; both superficial [SMS] and deep [SMD] portions) and the Triceps brachii (TB). Forty carcasses (10 carcasses per replication) were split and sides were assigned to either blast chill (BC, –32°C for 90 min, followed by spray chill at 2°C for 22.5 h) or conventional chill (CC, spray chilled at 2°C for 24 h) regimens. The LM from BC sides had lower (P < 0.05) temperature at 2 h postmortem (CC 21.8°C, BC 9.7°C), 4 h (CC 13.3°C, 3.8°C BC), 22 h (CC 4.2°C, BC 1.4°C), and 30 h (CC 0.4°C, BC –0.2°C). The LM pH in BC sides was higher at 4 h (CC 6.09, BC 6.34), 22 h (CC 5.81, BC 5.89), and 30 h (CC 5.68, BC 5.74) postmortem. The BC resulted in higher (P < 0.05) 30 h postmortem pH in the SM compared to the CC regime (CC 5.68, BC 5.74). The BC sides had increased (P < 0.05) purge in the PM (CC 0.48%, BC 0.74%) and increased (P < 0.05) cook loss in chops from the LM (CC 22.37%, BC 24.24%). The PM from BC sides were more juicy (CC 7.50, BC 8.30), less chewy (CC 2.80, BC 2.10), and more tender (CC 7.90, BC 8.60). Chops from the LM of BC sides had greater Warner-Bratzler shear force (CC 2.00, BC 2.30). Color was affected in the SM with BC sides showing darker color score (CC 3.00, BC 3.20) and redder Hunter a value (CC 16.35, BC 16.02). Chilling treatment did not affect sarcomere length in the LM. Treatment did not affect postmortem proteolysis in any cut. The response to chilling regimen is different across different muscles which may be caused by location, rate of chilling, and fiber type.


College Field Preceptor Contracted Partnership, Kimberly Procaccino Mba, Rd, Ldn, Melissa Faura Rd, Ldn, Ann Flickinger Ms, Rd, Ldn, Susan Gargano Rd, Ldn Oct 2019

College Field Preceptor Contracted Partnership, Kimberly Procaccino Mba, Rd, Ldn, Melissa Faura Rd, Ldn, Ann Flickinger Ms, Rd, Ldn, Susan Gargano Rd, Ldn

Clinical Nutrition Service

No abstract provided.