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Zoology

2013

Selected Works

Marcy J Souza

Articles 1 - 1 of 1

Full-Text Articles in Life Sciences

Pharmacokinetics Of Repeated Oral Administration Of Tramadol Hydrochloride In Hispaniolan Amazon Parrots (Amazona Ventralis), Marcy Souza, Lillian Gerhardt, Sherry Cox Jun 2013

Pharmacokinetics Of Repeated Oral Administration Of Tramadol Hydrochloride In Hispaniolan Amazon Parrots (Amazona Ventralis), Marcy Souza, Lillian Gerhardt, Sherry Cox

Marcy J Souza

Objective-To determine the pharmacokinetics of tramadol hydrochloride (30 mg/kg) following twice-daily oral administration in Hispaniolan Amazon parrots (Amazona ventralis). Animals-9 healthy adult Hispaniolan Amazon parrots. Procedures-Tramadol hydrochloride was administered to each parrot at a dosage of 30 mg/kg, PO, every 12 hours for 5 days. Blood samples were collected just prior to dose 2 on the first day of administration (day 1) and 5 minutes before and 10, 20, 30, 60, 90, 180, 360, and 720 minutes after the morning dose was given on day 5. Plasma was harvested from blood samples and analyzed by high-performance liquid chromatography ...