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California Institute of Integral Studies

Journal

Psychedelic

Articles 1 - 4 of 4

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Ketamine For Depression: A Mixed-Methods Study, Philip E. Wolfson Jul 2014

Ketamine For Depression: A Mixed-Methods Study, Philip E. Wolfson

International Journal of Transpersonal Studies

Prior studies have reported variously on the presence or absence of dissociative effects at subanesthtetic doses of ketamine administered for treatment-resistant depression. This mixedmethods study emulated the protocol used for the studies in question, with IV administration of 0.5mg/kg over 40 minutes with eight experienced ketamine users. Quantitative measures were generally insignificant since this was not a population reporting depression; blood pressure increased as expected by 20-30mm systolic and 6-20mm diastolic, falling rapidly by 20 minutes after completion of the infusion. Individual qualitative reports reports of relaxation, pleasant sensation, decreased cognitive function, and some disabling of ordinary capacities ...


Ketamine Psychedelic Psychotherapy: Focus On Its Pharmacology, Phenomenology, And Clinical Applications, Eli Kolp, Harris L. Friedman, Evgeny Krupitsky, Karl Jansen, Mark Sylvester, M. Scott Young, Anna Kolp Jul 2014

Ketamine Psychedelic Psychotherapy: Focus On Its Pharmacology, Phenomenology, And Clinical Applications, Eli Kolp, Harris L. Friedman, Evgeny Krupitsky, Karl Jansen, Mark Sylvester, M. Scott Young, Anna Kolp

International Journal of Transpersonal Studies

Meant to be an authoritative guide for psychiatrists and others interested in understanding and applying ketamine psychedelic psychotherapy (KPP), this paper focuses on its pharmacology, phenomenology, and clinical applications. Ketamine is a dissociative anesthetic widely used by physicians and veterinarians in the United States. In addition to its anesthetic and dissociative properties, ketamine also has a multitude of other psychological and pharmacological properties, which include analgesic, sedative, neuroprotective, anxiolytic, antidepressant, stimulant, euphoriant, and hallucinogenic effects. The literature on the clinical application of KPP is comprehensively reviewed, practical advice for using KPP is given, and the pharmacology and phenomenology of ketamine-induced ...


Ethnographic Accounts Of Ketamine Explorations In Psychedelic Culture, Kenneth Ring, Ralph Metzner, Philip E. Wolfson Jul 2014

Ethnographic Accounts Of Ketamine Explorations In Psychedelic Culture, Kenneth Ring, Ralph Metzner, Philip E. Wolfson

International Journal of Transpersonal Studies

Off-label use of ketamine as a mind-altering substance did not begin in the laboratory, but in the psychedelic culture that grew out of the 1960s counterculture movement. Whatever the risks and limitations of such experimentation, without them the remarkable therapeutic effects of the drug might well have gone unnoticed, and unresearched. The following personal accounts—both inspiring and cautionary—offer glimpses into the cultural contexts that found ketamine to be much more than a reliable anesthetic.


Psychoactive Substances And Paranormal Phenomena: A Comprehensive Review, David Luke Jan 2012

Psychoactive Substances And Paranormal Phenomena: A Comprehensive Review, David Luke

International Journal of Transpersonal Studies

This paper investigates the relationship between psychoactive substances and so-called paranormal

phenomena falling within the study of parapsychology. It is primarily concerned with extrasensory

perception (ESP)—telepathy, precognition, and clairvoyance—as well as out-of-body experiences

(OBEs) and near-death experiences (NDEs). Psychokinesis (PK), aura vision, encounter experiences,

and sleep paralysis only make a very limited contribution to this review as they are seldom related

to psychoactive drugs within the parapsychological literature. The paper borrows widely, but by no

means exhaustively, from parapsychology as well as transpersonal studies, anthropology, ethnobotany,

phytochemistry, psychiatry, psychotherapy, psychopharmacology, and neurobiology, particularly

neurochemistry. It is organized into ...