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Full-Text Articles in Philosophy

Blues Man On A Mojo Mission, Stephen Asma Nov 2002

Blues Man On A Mojo Mission, Stephen Asma

Stephen T Asma

Presents an article on rhythm and blues music in the U.S. Non-sponsorship of actual blues music in the House of Blues; Information on Mississippi bluesman Robert Johnson; Insights on using charms and amulets to improve guitar skills.


Applied Ethics In Animal Research: Philosophy, Regulation, And Laboratory Applications, John P. Gluck, Tony Dipasquale, F. Barbara Orlans Jan 2002

Applied Ethics In Animal Research: Philosophy, Regulation, And Laboratory Applications, John P. Gluck, Tony Dipasquale, F. Barbara Orlans

Purdue University Press Books

This volume is a collection of chapters all contributed by individuals who have presented their ideas at conferences and who take moderate stands with the use of animals in research. Specifically the chapters bear of the issues of: notions of the moral standings of animals, history of the methods of argumentation, knowledge of the animal mind, nature and value of regulatory structures, how respect for animals can be converted from theory to action in the laboratory. The chapters have been tempered by open discussion with individuals with different opinions and not audiences of true believers. It is the hope of ...


Pkcα Translocation And Actin Remodeling In Contracting A7r5 Smooth Muscle Cells, Chenwei Li Jan 2002

Pkcα Translocation And Actin Remodeling In Contracting A7r5 Smooth Muscle Cells, Chenwei Li

Theses, Dissertations and Capstones

Recent research indicates that protein kinase C (PKC) plays an important role in smooth muscle contraction. Because PKC activation and specificity of substrate phosphorylation is believed to be associated with the relocalization of the enzyme to specific cell sites, we first investigated the subcellular translocation of PKCα in A7r5 smooth muscle cells by confocal microscopy through use of standard immunohistologic staining and PKCα - enhanced green fluorescent protein (PKCα -EGFP) fusion protein expression. PKCα was diffusely distributed throughout the cytosol in the unstimulated A7r5 cell. Upon stimulation with phorbol 12, 13 dibutyrate (PDBu), PKCα was translocated primarily to either the perinuclear ...


Rethinking Mechanistic Explanation, Stuart Glennan Jan 2002

Rethinking Mechanistic Explanation, Stuart Glennan

Scholarship and Professional Work - LAS

Philosophers of science typically associate the causal-mechanical view of scientific explanation with the work of Railton and Salmon. In this paper I shall argue that the defects of this view arise from an inadequate analysis of the concept of mechanism. I contrast Salmon's account of mechanisms in terms of the causal nexus with my own account of mechanisms, in which mechanisms are viewed as complex systems. After describing these two concepts of mechanism, I show how the complex-systems approach avoids certain objections to Salmon's account of causal-mechanical explanation. I conclude by discussing how mechanistic explanations can provide understanding ...