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Full-Text Articles in Arts and Humanities

Impact Of Cyclooxygenase Inhibitors In The Women's Health Initiative Hormone Trials: Secondary Analysis Of A Randomized Trial, Judith Hsia, Joann E. Manson, Lewis H. Kuller, Mary B. Pettinger, John H. Choe, Robert D. Langer, Marian C. Limacher, Albert Oberman, Judith K. Ockene, Mary Jo O'Sullivan, Jennifer G. Robinson Sep 2006

Impact Of Cyclooxygenase Inhibitors In The Women's Health Initiative Hormone Trials: Secondary Analysis Of A Randomized Trial, Judith Hsia, Joann E. Manson, Lewis H. Kuller, Mary B. Pettinger, John H. Choe, Robert D. Langer, Marian C. Limacher, Albert Oberman, Judith K. Ockene, Mary Jo O'Sullivan, Jennifer G. Robinson

Women’s Health Research Faculty Publications

OBJECTIVES: We evaluated the hypothesis that cyclooxygenase (COX) inhibitor use might have counteracted a beneficial effect of postmenopausal hormone therapy, and account for the absence of cardioprotection in the Women's Health Initiative hormone trials. Estrogen increases COX expression, and inhibitors of COX such as nonsteroidal anti-inflammatory agents appear to increase coronary risk, raising the possibility of a clinically important interaction in the trials.

DESIGN: The hormone trials were randomized, double-blind, and placebo-controlled. Use of nonsteroidal anti-inflammatory drugs was assessed at baseline and at years 1, 3, and 6.

SETTING: The Women's Health Initiative hormone trials were conducted at ...


Changing The Face Of Medicine: One Historian's Experience As A Curator, Ellen S. More Jul 2006

Changing The Face Of Medicine: One Historian's Experience As A Curator, Ellen S. More

Library Publications

In the spring of 2001 during a meeting of the American Association for the History of Medicine, Elizabeth Fee, Chief of the History of Medicine Division of the National Library of Medicine (NLM), invited me to become the Visiting Curator for a new exhibition they intended to present on the history of women physicians. It was the first full-scale exhibition ever devoted to that subject by the NLM. After more than two years’ preparation, the exhibition, “Changing the Face of Medicine: Celebrating America’s Women Physicians,” opened in April 2003 and continued on display at the NLM for more than ...


Identifying Strategies To Improve Access To Credible And Relevant Information For Public Health Professionals: A Qualitative Study, Nancy R. Lapelle, Roger S. Luckmann, E. Hatheway Simpson, Elaine Russo Martin Apr 2006

Identifying Strategies To Improve Access To Credible And Relevant Information For Public Health Professionals: A Qualitative Study, Nancy R. Lapelle, Roger S. Luckmann, E. Hatheway Simpson, Elaine Russo Martin

Library Publications

Background Movement towards evidence-based practices in many fields suggests that public health (PH) challenges may be better addressed if credible information about health risks and effective PH practices is readily available. However, research has shown that many PH information needs are unmet. In addition to reviewing relevant literature, this study performed a comprehensive review of existing information resources and collected data from two representative PH groups, focusing on identifying current practices, expressed information needs, and ideal systems for information access. Methods Nineteen individual interviews were conducted among employees of two domains in a state health department – communicable disease control and ...