Open Access. Powered by Scholars. Published by Universities.®

Arts and Humanities Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 7 of 7

Full-Text Articles in Arts and Humanities

A Chronology For The Identification And Disclosure Of Adverse Effects Of Succinylcholine, Lisa Huang, Christine N. Sang, Manisha S. Desai Jul 2018

A Chronology For The Identification And Disclosure Of Adverse Effects Of Succinylcholine, Lisa Huang, Christine N. Sang, Manisha S. Desai

Anesthesiology and Perioperative Medicine Publications

Background: New therapies are created to address specific problems and enjoy popularity as they enter widespread clinical use. Broader use can reveal unknown adverse effects and impact the life cycle significantly. Succinylcholine, a depolarizing neuromuscular blocker, was the product of decades of research surrounding the ancient compound, curare. It was introduced into practice in the 1940s by Burroughs Wellcome and Company (BW Co.) and was welcomed due to its rapidly acting muscle relaxation effects. Global clinical use revealed adverse effects, both minor and major, in particular, hyperkalemia and malignant hyperthermia. We investigated when practitioners and the manufacturer became aware of ...


William James Morton (1845 – 1920): Like Father, Like Son?, Antonio Aponte-Feliciano, Sukumar P. Desai, Manisha S. Desai Apr 2013

William James Morton (1845 – 1920): Like Father, Like Son?, Antonio Aponte-Feliciano, Sukumar P. Desai, Manisha S. Desai

Anesthesiology and Perioperative Medicine Publications

William Thomas Green Morton, the man most commonly associated with the introduction of anesthesia in 1846, fathered William James Morton. William James Morton’s contributions to society were substantial. He conducted pioneering work in radiology, radiation oncology, and therapeutic electricity. He authored numerous textbooks and articles, and he was an editor of a journal on human behavior. His expertise on diamond mining led to an error in judgment that resulted in a felony conviction. We examine his career and contributions to society, and consider his career in light of his father, William Thomas Green Morton.


Medical History For Anesthesiologists: Continuation Of A Primer, Manisha S. Desai, Sukumar P. Desai Apr 2013

Medical History For Anesthesiologists: Continuation Of A Primer, Manisha S. Desai, Sukumar P. Desai

Anesthesiology and Perioperative Medicine Publications

Editor’s note: The absence of a recognized formal curriculum in anesthesia history means that many of us have known and unknown gaps in our knowledge. These gaps limit our ability to understand how things came to be, how things may become and how we can affect the future. I have asked Dr. Manisha Desai and Dr. Sukumar Desai to provide a primer on the history of medicine and anesthesia history. The goals of this primer are to educate and to help individuals target future study. Below is the second article in a continuing series.


Horace Wells Memorials In The City Of Hartford, Connecticut, Antonio Aponte-Feliciano, Sukumar P. Desai, Manisha S. Desai Oct 2012

Horace Wells Memorials In The City Of Hartford, Connecticut, Antonio Aponte-Feliciano, Sukumar P. Desai, Manisha S. Desai

Anesthesiology and Perioperative Medicine Publications

Introduction: Hartford, capital city of Connecticut was where Horace Wells conducted most of his work on the only anesthetic gas still used in clinical practice since the 19th century – nitrous oxide. Wells was born and raised in Hartford, Vermont, studied dentistry in Boston and established his practice in Hartford, Connecticut. Various icons celebrating Wells’ unique contributions in discovering the analgesic properties of nitrous oxide are located throughout this city.

Materials and Methods: We consulted staff at Connecticut Historical Society (CHS) and at Hartford Medical Society to help identify sites and artifacts in Hartford that honor Horace Wells. Thereafter, we visited ...


Primer On Medical History For Anesthesiologists: Introduction, Manisha S. Desai, Sukumar P. Desai Oct 2012

Primer On Medical History For Anesthesiologists: Introduction, Manisha S. Desai, Sukumar P. Desai

Anesthesiology and Perioperative Medicine Publications

Editor’s note: The absence of a recognized formal curriculum in anesthesia history means that many of us have known and unknown gaps in our knowledge. These gaps limit our ability to understand how things came to be, how things may become and how we can affect the future. I have asked Dr. Manisha Desai and Dr. Sukumar Desai to provide a survey of medical history. The goals of this primer are 1) to educate, and 2) to help individuals target future study. Below is the first article in a continuing series.


The First Use Of Ether Anaesthesia In India -- A Plea For More Information, Sukumar P. Desai, Manisha S. Desai Dec 2009

The First Use Of Ether Anaesthesia In India -- A Plea For More Information, Sukumar P. Desai, Manisha S. Desai

Anesthesiology and Perioperative Medicine Publications

No abstract provided.


The Discovery Of Modern Anaesthesia – Contributions Of Davy, Clarke, Long, Wells And Morton, Sukumar P. Desai, Manisha S. Desai, Chandrakant S. Pandav Dec 2007

The Discovery Of Modern Anaesthesia – Contributions Of Davy, Clarke, Long, Wells And Morton, Sukumar P. Desai, Manisha S. Desai, Chandrakant S. Pandav

Anesthesiology and Perioperative Medicine Publications

While many may argue as to who deserves the most credit for the discovery of modern anaesthesia, events in the late 18 th and early 19 th centuries led to the introduction and development of modern anaesthetic techniques. English physicist and chemist Humphry Davy [1778-1829] first became aware of the sedative and analgesic properties of nitrous oxide in 1795. Although he never experimented with the drug during a surgical procedure, he was the first to suggest that it would be beneficial in relieving pain during surgical procedures. The mind-altering properties of nitrous oxide and ether were often abused for recreational ...